{"id":13381,"date":"2024-08-23T00:31:43","date_gmt":"2024-08-22T22:31:43","guid":{"rendered":"https:\/\/valintermed.com\/?p=13381"},"modified":"2024-08-23T00:31:43","modified_gmt":"2024-08-22T22:31:43","slug":"sindrom-vernera","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/sindrom-vernera\/","title":{"rendered":"Werner's syndrome"},"content":{"rendered":"
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Werner syndrome, also known as premature aging syndrome, is a rare genetic disorder characterized by accelerated aging, which manifests itself in a number of clinical signs associated with premature aging of tissues and organs. The main symptoms of the disease include premature development of atherosclerosis, diabetes, osteoporosis, loss of muscle mass, and various skin changes, including loss of elasticity and wrinkles. The syndrome is caused by mutations in the WRN gene, which is responsible for DNA repair and maintaining genomic stability. This condition manifests itself after the age of 30, although clinical signs may vary from patient to patient.<\/p>\n

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