{"id":13325,"date":"2024-08-23T01:26:38","date_gmt":"2024-08-22T23:26:38","guid":{"rendered":"https:\/\/valintermed.com\/?p=13325"},"modified":"2024-08-23T01:26:38","modified_gmt":"2024-08-22T23:26:38","slug":"gipoplaziya-mozzhechka-svyazannaya-s-vldlr","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/hypoplasia-of-the-mozzhechka-associated-with-vldlr\/","title":{"rendered":"Cerebellar hypoplasia associated with VLDLR"},"content":{"rendered":"
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VLDLR-associated cerebellar hypoplasia is a rare neurological disorder characterized by underdevelopment of the cerebellum, resulting in a variety of problems with motor coordination, balance, and motor function. The condition is associated with a mutation in the VLDLR (Very Low Density Lipoprotein Receptor) gene, which plays a key role in the development of the central nervous system, particularly in the formation of neurons and the proliferation of neuronal cells. Deficiency of VLDLR receptors leads to disruption of signal transmission, which in turn impedes normal development of the cerebellum. The disease can manifest itself in both childhood and adulthood and is characterized by a variety of clinical manifestations that require careful diagnosis and an individual approach to treatment.<\/p>\n

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