{"id":13280,"date":"2024-08-23T02:15:30","date_gmt":"2024-08-23T00:15:30","guid":{"rendered":"https:\/\/valintermed.com\/?p=13280"},"modified":"2024-09-21T18:08:46","modified_gmt":"2024-09-21T16:08:46","slug":"trihotiodistrofiya","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/trichotiodystrophy\/","title":{"rendered":"Trichothiodystrophy"},"content":{"rendered":"
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Trichothiodystrophy (TTD) is a rare genetic disorder that causes severe changes in the structure and function of hair, skin, and nails. The underlying pathogenesis of the disease is related to disruption of keratin synthesis, which results in hair that becomes brittle, thin, and dull. These changes in hair structure may be accompanied by dermatological manifestations, including skin irritation and melanin abnormalities in pigmentation. The disorder is inherited in an autosomal recessive manner and is associated with mutations in genes responsible for keratin structure and function. It is important to note that trichothiodystrophy may also affect other tissues of the body, causing various dermatological problems and hair growth disorders.<\/p>\n

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