{"id":13075,"date":"2024-08-23T05:40:01","date_gmt":"2024-08-23T03:40:01","guid":{"rendered":"https:\/\/valintermed.com\/?p=13075"},"modified":"2024-08-23T05:40:01","modified_gmt":"2024-08-23T03:40:01","slug":"spinotserebellyarnaya-ataksiya-tip-8","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/spinal-cord-injury-tip-8\/","title":{"rendered":"Spinocerebellar ataxia type 8"},"content":{"rendered":"
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Spinocerebellar ataxia type 8 (SCA8) is an inherited neurodegenerative disorder that is primarily characterized by impaired coordination and balance. The main clinical manifestations are ataxias, which can affect both the cerebellum and some areas of the spinal cord. SCA8 can also manifest itself with symptoms such as asynergia, dysmetria, tremor, and decreased muscle tone, which leads to significant functional limitations in patients. This disease is caused by the expansion of repetitive nucleotide sequences in the ATXN8 gene, which leads to the formation of toxic proteins. The onset of the disease usually occurs in the middle age category, but can vary from adrenal insufficiency to moderate progressive disability. <\/p>\n

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