{"id":13059,"date":"2024-08-23T05:55:37","date_gmt":"2024-08-23T03:55:37","guid":{"rendered":"https:\/\/valintermed.com\/?p=13059"},"modified":"2024-08-23T05:55:37","modified_gmt":"2024-08-23T03:55:37","slug":"spinotserebellyarnaya-ataksiya-tip-13","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/spinal-cord-injury-tip-13\/","title":{"rendered":"Spinocerebellar ataxia type 13"},"content":{"rendered":"<div class=\"fpm_start\"><\/div>\n<p>Spinocerebellar ataxia type 13 (SCA13) is an inherited neurodegenerative disorder belonging to the group of spinocerebellar ataxias, characterized by progressive atrophy of the cerebellum and other structures of the central nervous system. The main manifestations of the disease include impaired motor coordination, ataxia, balance deficits, and severe dysfunction of the extrapyramidal system. These symptoms result from damage to the cerebellum, which plays a key role in regulating movement and maintaining balance. Although the severity of symptoms can vary, SCA13 typically results in a significant deterioration in the quality of life and loss of independence in patients as the disease progresses, affecting their motor skills and basic functions.<\/p>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_83 counter-flat ez-toc-counter ez-toc-light-blue ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Content<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 eztoc-toggle-hide-by-default' ><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/spinal-cord-injury-tip-13\/#%D0%98%D1%81%D1%82%D0%BE%D1%80%D0%B8%D1%8F_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F_%D0%B8_%D0%B8%D0%BD%D1%82%D0%B5%D1%80%D0%B5%D1%81%D0%BD%D1%8B%D0%B5_%D0%B8%D1%81%D1%82%D0%BE%D1%80%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B8%D0%B5_%D1%84%D0%B0%D0%BA%D1%82%D1%8B\" >History of the disease and interesting historical facts<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/spinal-cord-injury-tip-13\/#%D0%AD%D0%BF%D0%B8%D0%B4%D0%B5%D0%BC%D0%B8%D0%BE%D0%BB%D0%BE%D0%B3%D0%B8%D1%8F\" >Epidemiology<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/spinal-cord-injury-tip-13\/#%D0%93%D0%B5%D0%BD%D0%B5%D1%82%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B0%D1%8F_%D0%BF%D1%80%D0%B5%D0%B4%D1%80%D0%B0%D1%81%D0%BF%D0%BE%D0%BB%D0%BE%D0%B6%D0%B5%D0%BD%D0%BD%D0%BE%D1%81%D1%82%D1%8C_%D0%BA_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%BC%D1%83_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8E\" >Genetic predisposition to this disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/spinal-cord-injury-tip-13\/#%D0%A4%D0%B0%D0%BA%D1%82%D0%BE%D1%80%D1%8B_%D1%80%D0%B8%D1%81%D0%BA%D0%B0_%D0%B2%D0%BE%D0%B7%D0%BD%D0%B8%D0%BA%D0%BD%D0%BE%D0%B2%D0%B5%D0%BD%D0%B8%D1%8F_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >Risk factors for the development of this disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/spinal-cord-injury-tip-13\/#%D0%94%D0%B8%D0%B0%D0%B3%D0%BD%D0%BE%D1%81%D1%82%D0%B8%D0%BA%D0%B0_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >Diagnosis of this disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/spinal-cord-injury-tip-13\/#%D0%9B%D0%B5%D1%87%D0%B5%D0%BD%D0%B8%D0%B5\" >Treatment<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/spinal-cord-injury-tip-13\/#%D0%A1%D0%BF%D0%B8%D1%81%D0%BE%D0%BA_%D0%BB%D0%B5%D0%BA%D0%B0%D1%80%D1%81%D1%82%D0%B2_%D0%BF%D1%80%D0%B8%D0%BC%D0%B5%D0%BD%D1%8F%D0%B5%D0%BC%D1%8B%D1%85_%D0%B4%D0%BB%D1%8F_%D0%BB%D0%B5%D1%87%D0%B5%D0%BD%D0%B8%D1%8F_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >List of medications used to treat this disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/spinal-cord-injury-tip-13\/#%D0%9C%D0%BE%D0%BD%D0%B8%D1%82%D0%BE%D1%80%D0%B8%D0%BD%D0%B3_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >Disease monitoring<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/spinal-cord-injury-tip-13\/#%D0%92%D0%BE%D0%B7%D1%80%D0%B0%D1%81%D1%82%D0%BD%D1%8B%D0%B5_%D0%BE%D1%81%D0%BE%D0%B1%D0%B5%D0%BD%D0%BD%D0%BE%D1%81%D1%82%D0%B8_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >Age-related features of the disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/spinal-cord-injury-tip-13\/#%D0%92%D0%BE%D0%BF%D1%80%D0%BE%D1%81%D1%8B_%D0%B8_%D0%BE%D1%82%D0%B2%D0%B5%D1%82%D1%8B\" >Questions and Answers<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"%D0%98%D1%81%D1%82%D0%BE%D1%80%D0%B8%D1%8F_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F_%D0%B8_%D0%B8%D0%BD%D1%82%D0%B5%D1%80%D0%B5%D1%81%D0%BD%D1%8B%D0%B5_%D0%B8%D1%81%D1%82%D0%BE%D1%80%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B8%D0%B5_%D1%84%D0%B0%D0%BA%D1%82%D1%8B\"><\/span>History of the disease and interesting historical facts<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Spinocerebellar ataxia type 13 was first described in the late 20th century, but its genetic basis was only finally determined in 2005, when researchers identified a mutation in the KCNJ6 gene, which codes for a potassium channel. Initial cases of the disease were noted among individual families in certain regions, which led to the assumption that the pathology was hereditary. An article published in the journal Nature Genetics in 2005 provided the first evidence of the relationship between the gene mutation and the manifestations of the disease. Interestingly, SCA13 was initially mistakenly attributed to other types of ataxia, and only with the development of genetic research were we able to characterize the disease and its pathogenesis in more detail.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%AD%D0%BF%D0%B8%D0%B4%D0%B5%D0%BC%D0%B8%D0%BE%D0%BB%D0%BE%D0%B3%D0%B8%D1%8F\"><\/span>Epidemiology<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The epidemiology of spinocerebellar ataxia type 13 remains poorly understood. The prevalence of the disorder appears to vary across ethnic groups and geographic regions. In the general population, SCA13 is extremely rare. It has been shown that the highest incidence is in certain populations with strong genetic predispositions. A 2018 study reported that among people with hereditary ataxias, SCA13 accounts for between 0.5% and 2% of all cases. However, due to the lack of large-scale epidemiological studies, the exact prevalence rates remain uncertain.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%93%D0%B5%D0%BD%D0%B5%D1%82%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B0%D1%8F_%D0%BF%D1%80%D0%B5%D0%B4%D1%80%D0%B0%D1%81%D0%BF%D0%BE%D0%BB%D0%BE%D0%B6%D0%B5%D0%BD%D0%BD%D0%BE%D1%81%D1%82%D1%8C_%D0%BA_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%BC%D1%83_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8E\"><\/span>Genetic predisposition to this disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The leading cause of spinocerebellar ataxia type 13 is a mutation in the KCNJ6 gene, which codes for the retentive potassium channel (K2P). These mutations cause channel dysfunction and disrupt normal electrical activity of neurons in areas of the brain responsible for motor coordination. The gene is known to be located on chromosome 8, and both point mutations and more complex genetic variations have been found. Genetic studies also suggest that the disease may be inherited in a dominant manner. However, the manifestations of SCA13 may vary, with some carriers of the mutation being asymptomatic (latent). This highlights the importance of genetic counseling, especially for families with a history of the disease.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%A4%D0%B0%D0%BA%D1%82%D0%BE%D1%80%D1%8B_%D1%80%D0%B8%D1%81%D0%BA%D0%B0_%D0%B2%D0%BE%D0%B7%D0%BD%D0%B8%D0%BA%D0%BD%D0%BE%D0%B2%D0%B5%D0%BD%D0%B8%D1%8F_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>Risk factors for the development of this disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Although SCA13 is primarily genetic, several environmental factors may interact with genetic predisposition. These include:<\/p>\n<ul>\n<li>Heredity - having a history of the disease in a family greatly increases the risk of passing on the mutation.<\/li>\n<li>Age - symptoms often appear in adulthood, although the first symptoms may also appear in adolescence.<\/li>\n<li>Certain chemical factors - There is a hypothetical link between exposure to certain toxins and an acceleration of symptoms in genetically susceptible individuals.<\/li>\n<li>Psycho-emotional factors - stressful situations can cause an exacerbation or acceleration of the progression of symptoms.<\/li>\n<li>Infectious agents - in rare cases, exacerbation of symptoms may be observed after viral infections, which requires further investigation.<\/li>\n<\/ul>\n<h2><span class=\"ez-toc-section\" id=\"%D0%94%D0%B8%D0%B0%D0%B3%D0%BD%D0%BE%D1%81%D1%82%D0%B8%D0%BA%D0%B0_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>Diagnosis of this disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Diagnosis of spinocerebellar ataxia type 13 begins with a full medical history and neurological examination, during which the main symptoms of the disease are examined. The most characteristic symptoms may include:<\/p>\n<ul>\n<li>Ataxia - involuntary, uncoordinated movements;<\/li>\n<li>Dysarthria is a speech disorder;<\/li>\n<li>Impaired balance and coordination;<\/li>\n<li>Tremor - shaking of the limbs;<\/li>\n<li>Decreased muscle tone.<\/li>\n<\/ul>\n<p>Laboratory testing includes genetic testing to confirm the presence of a mutation in the KCNJ6 gene. Radiological examinations such as MRI of the brain can visualize atrophy of the cerebellum and other structures, which also helps in diagnosing the disease. Evaluation of various motor and cognitive functions helps in differential diagnosis, excluding other neurodegenerative and genetic disorders such as Huntington&#039;s disease and Friedreich&#039;s disease.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%9B%D0%B5%D1%87%D0%B5%D0%BD%D0%B8%D0%B5\"><\/span>Treatment<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Treatment of spinocerebellar ataxia type 13 currently has no specific etiologic approach, as the disease is progressive and irreversible. Symptomatic treatment usually includes the use of various methods aimed at improving the quality of life and supporting the patient&#039;s functions:<\/p>\n<ul>\n<li>Pharmacological treatment includes drugs that improve neurotransmitter transmission and reduce the symptoms of ataxia and tremor.<\/li>\n<li>Physical therapy and rehabilitation help improve coordination and maintain physical activity.<\/li>\n<li>Cognitive therapy may be helpful for patients with cognitive impairment.<\/li>\n<li>Surgical treatment may be considered in cases of serious complications, such as severe balance disorders.<\/li>\n<\/ul>\n<h2><span class=\"ez-toc-section\" id=\"%D0%A1%D0%BF%D0%B8%D1%81%D0%BE%D0%BA_%D0%BB%D0%B5%D0%BA%D0%B0%D1%80%D1%81%D1%82%D0%B2_%D0%BF%D1%80%D0%B8%D0%BC%D0%B5%D0%BD%D1%8F%D0%B5%D0%BC%D1%8B%D1%85_%D0%B4%D0%BB%D1%8F_%D0%BB%D0%B5%D1%87%D0%B5%D0%BD%D0%B8%D1%8F_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>List of medications used to treat this disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>There are currently no specific medications to treat SCA13. However, the following may be used to reduce symptoms:<\/p><script data-noptimize=\"\" data-wpfc-render=\"false\">\nfpm_start( \"true\" );\n<\/script>\n\n<ul>\n<li>Anti-inflammatory drugs;<\/li>\n<li>Antidepressants and anxiolytics to improve the psycho-emotional state;<\/li>\n<li>Drugs to improve nervous system function, such as inositol and glycine.<\/li>\n<li>Contains antioxidants and neuroprotectors to support overall health.<\/li>\n<\/ul>\n<h2><span class=\"ez-toc-section\" id=\"%D0%9C%D0%BE%D0%BD%D0%B8%D1%82%D0%BE%D1%80%D0%B8%D0%BD%D0%B3_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>Disease monitoring<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Monitoring the condition of patients with SCA13 requires regular visits to a neurologist, who will track the progression of the disease and adjust treatment. Monitoring steps include:<\/p>\n<ul>\n<li>Routine neurological examinations;<\/li>\n<li>Genetic studies to assess changes in mutations;<\/li>\n<li>Measurement of motor functions and coordination.<\/li>\n<\/ul>\n<p>The prognosis depends on the severity of symptoms at diagnosis, but they typically progress over time. Complications can include profound disability, requiring significant support from medical staff and family members.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%92%D0%BE%D0%B7%D1%80%D0%B0%D1%81%D1%82%D0%BD%D1%8B%D0%B5_%D0%BE%D1%81%D0%BE%D0%B1%D0%B5%D0%BD%D0%BD%D0%BE%D1%81%D1%82%D0%B8_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>Age-related features of the disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Spinocerebellar ataxia type 13 has some age-related features in its course. The disease can begin in different age groups, from adolescence to maturity. In young people, less pronounced symptoms are often observed, while in older people, the disease is accompanied by more serious motor disorders that worsen the quality of life. It is important to note that the hereditary nature of the disease emphasizes their genetic predisposition, which can manifest itself more actively in subsequent generations.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%92%D0%BE%D0%BF%D1%80%D0%BE%D1%81%D1%8B_%D0%B8_%D0%BE%D1%82%D0%B2%D0%B5%D1%82%D1%8B\"><\/span>Questions and Answers<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<ul>\n<li><strong>What are the main symptoms of SCA13?<\/strong> The main symptoms are ataxia, dysarthria, balance disorders, tremors and decreased muscle tone.<\/li>\n<li><strong>What is the inheritance mechanism of SCA13?<\/strong> SCA13 is inherited in a dominant manner, meaning that one parent with the mutation can pass it on to their offspring.<\/li>\n<li><strong>What tests are needed to diagnose SCA13?<\/strong> Diagnosis requires a neurological examination, genetic testing, and MRI of the brain.<\/li>\n<li><strong>What is the life expectancy with SCA13?<\/strong> Life expectancy may vary, but the disease typically results in significant functional limitations and disability.<\/li>\n<li><strong>Can SCA13 be prevented?<\/strong> Because the disease is genetic, there is currently no known way to prevent it. Genetic counseling can help identify risks for future generations.<\/li>\n<\/ul>\n<div class=\"fpm_end\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Spinocerebellar ataxia type 13 (SCA13) is an inherited neurodegenerative disorder belonging to the group of spinocerebellar ataxias, characterized by progressive atrophy of the cerebellum and<\/p>","protected":false},"author":1,"featured_media":23301,"comment_status":"open","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[298],"tags":[],"class_list":["post-13059","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medlibrary"],"_links":{"self":[{"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/posts\/13059","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/comments?post=13059"}],"version-history":[{"count":1,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/posts\/13059\/revisions"}],"predecessor-version":[{"id":13861,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/posts\/13059\/revisions\/13861"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/media\/23301"}],"wp:attachment":[{"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/media?parent=13059"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/categories?post=13059"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/tags?post=13059"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}