{"id":13057,"date":"2024-08-23T05:56:25","date_gmt":"2024-08-23T03:56:25","guid":{"rendered":"https:\/\/valintermed.com\/?p=13057"},"modified":"2024-08-23T05:56:25","modified_gmt":"2024-08-23T03:56:25","slug":"spinotserebellyarnaya-ataksiya-tip-11","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/spinal-cord-injury-tip-11\/","title":{"rendered":"Spinocerebellar ataxia type 11"},"content":{"rendered":"
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Spinocerebellar ataxia type 11 (SCA11) is an inherited neurodegenerative disorder characterized by progressive loss of motor coordination, balance, and possible speech and cognitive impairment. The disorder belongs to the group of spinocerebellar ataxias and spinal and cerebellar dysplasias. The main clinical manifestations of SCA11 are ataxia, dysarthria, and hypotonia, which progress over time and lead to a significant deterioration in the quality of life of patients. The disease is associated with degeneration of neurons in the cerebellum and spinal cord, which affects motor functions. The pathogenetic mechanism of this disorder, like many other types of spinocerebellar ataxias, is a protein abnormality associated with a gene mutation, which leads to disruption of the integrity of neural tissue and progressive neurological symptoms.<\/p>\n

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