{"id":13050,"date":"2024-08-23T06:05:24","date_gmt":"2024-08-23T04:05:24","guid":{"rendered":"https:\/\/valintermed.com\/?p=13050"},"modified":"2024-08-23T06:05:24","modified_gmt":"2024-08-23T04:05:24","slug":"spinalnaya-myshechnaya-atrofiya-tip-1","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/spinal-myocardial-atrophy-tip-1\/","title":{"rendered":"Spinal muscular atrophy type 1"},"content":{"rendered":"
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Spinal muscular atrophy (SMA) type 1, also known as Werdnig-Hoffmann disease, is a genetic disorder characterized by progressive weakness and wasting of skeletal muscles. It is caused by a failure of motor neurons in the anterior horns of the spinal cord, which disrupts the transmission of nerve impulses to the muscles. SMA type 1 manifests itself in early childhood, usually before 6 months, and is severe in most cases. Symptoms include muscle weakness, difficulty moving, and significant fatigue with physical activity, which significantly limits the ability to move independently and can lead to severe complications such as pneumonia and respiratory failure.<\/p>\n

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