{"id":13049,"date":"2024-08-23T06:05:47","date_gmt":"2024-08-23T04:05:47","guid":{"rendered":"https:\/\/valintermed.com\/?p=13049"},"modified":"2024-08-23T06:05:47","modified_gmt":"2024-08-23T04:05:47","slug":"spinalnaya-myshechnaya-atrofiya-s-artrogripozom","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/spinal-myocardial-atrophy-with-arthropathy\/","title":{"rendered":"Spinal muscular atrophy with arthrogryposis"},"content":{"rendered":"
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Spinal muscular atrophy (SMA) with arthrogryposis is a rare genetic disorder characterized by progressive skeletal muscle wasting due to motor neuron dysfunction and joint deformities caused by insufficient muscle tissue development. The condition may manifest itself in childhood and is associated with comorbid manifestations such as contractures and limitation of motion. Although SMA and arthrogryposis are distinct categories of disorders, their coexistence leads to significant functional disabilities and decreased quality of life in patients. The underlying cause of SMA is a genetic mutation associated with loss or alteration of motor neuron function, which can lead to a variety of clinical symptoms and consequences.<\/p>\n

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