{"id":13039,"date":"2024-08-23T06:15:54","date_gmt":"2024-08-23T04:15:54","guid":{"rendered":"https:\/\/valintermed.com\/?p=13039"},"modified":"2024-08-23T06:15:54","modified_gmt":"2024-08-23T04:15:54","slug":"spasticheskaya-paraplegiya-2-tipa","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/spastic-paraplegia-type-2\/","title":{"rendered":"Spastic paraplegia type 2"},"content":{"rendered":"
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Spastic paraplegia type 2 (SPG2), also known as spastic paraplegia due to a SPAST gene mutation, is an inherited neurological disorder characterized by progressive weakness and spasticity of the lower limbs. The disease is caused by damage to the corticospinal tracts, which leads to impaired muscle tone and difficulty in movement. SPG2 is a form of spastic paraplegia belonging to a group of hereditary spastic paraparesis, and is characterized by predominant symptoms of spasticity, rigidity, and impaired motor coordination. The onset of the disease often occurs in childhood or adolescence, although cases of later onset are possible. <\/p>\n

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