{"id":13022,"date":"2024-08-23T06:31:38","date_gmt":"2024-08-23T04:31:38","guid":{"rendered":"https:\/\/valintermed.com\/?p=13022"},"modified":"2024-08-23T06:31:38","modified_gmt":"2024-08-23T04:31:38","slug":"skleredema","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/sclerodema\/","title":{"rendered":"Scleredema"},"content":{"rendered":"
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Scleredema is a systemic disease of connective tissue characterized by increased collagen productivity and other metabolic disorders in the skin and internal organs. The most noticeable clinical manifestations of scleredema are thickening and compaction of the skin, as well as manifestations from the vascular system and internal organs. The disease can manifest itself in various forms: localized, systemic and diffuse, which affects the tactics of diagnosis and treatment, as well as the prognosis. The etiological factors of the disease remain unclear, but it is assumed that both genetic and external factors can influence its development.<\/p>\n

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