{"id":13015,"date":"2024-08-23T06:40:27","date_gmt":"2024-08-23T04:40:27","guid":{"rendered":"https:\/\/valintermed.com\/?p=13015"},"modified":"2024-08-23T06:40:27","modified_gmt":"2024-08-23T04:40:27","slug":"sistemnyy-mastotsitoz","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/systemic-mastocytosis\/","title":{"rendered":"Systemic mastocytosis"},"content":{"rendered":"
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Systemic mastocytosis is a heterogeneous group of diseases characterized by an increase in the number of mast cells in various tissues of the body. These cells play a key role in the immune response and inflammatory reactions, and are also involved in allergic processes. The main feature of systemic mastocytosis is the abnormal accumulation of mast cells in the skin, bones, liver, spleen and other organs, which can lead to numerous clinical manifestations. The disease can occur in various forms - from less dangerous with insolation and limited symptoms to more serious ones with manifestations of systemic disorders and even life-threatening conditions. Clinical manifestations of systemic mastocytosis vary and can be caused by both dysfunction of the mast cells themselves and the substances they secrete.<\/p>\n

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