{"id":13012,"date":"2024-08-23T06:41:36","date_gmt":"2024-08-23T04:41:36","guid":{"rendered":"https:\/\/valintermed.com\/?p=13012"},"modified":"2024-08-23T06:41:36","modified_gmt":"2024-08-23T04:41:36","slug":"siringomieliya","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/siringomieliya\/","title":{"rendered":"Syringomyelia"},"content":{"rendered":"<div class=\"fpm_start\"><\/div>\n<p>Syringomyelia is a neurological disorder characterized by the formation of cysts filled with spinal fluid (syringes) in the spinal cord. These cysts can gradually enlarge and cause destruction of nerve tissue, leading to various neurological symptoms. The disease is often associated with other pathologies, such as Kimmer&#039;s anomalies, Arnold-Chiari malformations, or spinal injuries. The most common clinical manifestations are pain, loss of sensation, muscle weakness, and impaired motor function. Lack of timely diagnosis and treatment can lead to significant complications, increasing the severity of the patient&#039;s condition.<\/p>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_85 counter-flat ez-toc-counter ez-toc-light-blue ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Content<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" 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href=\"https:\/\/valintermed.com\/en\/medlibrary\/siringomieliya\/#%D0%98%D1%81%D1%82%D0%BE%D1%80%D0%B8%D1%8F_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F_%D0%B8_%D0%B8%D0%BD%D1%82%D0%B5%D1%80%D0%B5%D1%81%D0%BD%D1%8B%D0%B5_%D0%B8%D1%81%D1%82%D0%BE%D1%80%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B8%D0%B5_%D1%84%D0%B0%D0%BA%D1%82%D1%8B\" >History of the disease and interesting historical facts<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/siringomieliya\/#%D0%AD%D0%BF%D0%B8%D0%B4%D0%B5%D0%BC%D0%B8%D0%BE%D0%BB%D0%BE%D0%B3%D0%B8%D1%8F\" >Epidemiology<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/siringomieliya\/#%D0%93%D0%B5%D0%BD%D0%B5%D1%82%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B0%D1%8F_%D0%BF%D1%80%D0%B5%D0%B4%D1%80%D0%B0%D1%81%D0%BF%D0%BE%D0%BB%D0%BE%D0%B6%D0%B5%D0%BD%D0%BD%D0%BE%D1%81%D1%82%D1%8C_%D0%BA_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%BC%D1%83_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8E\" >Genetic predisposition to this disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/siringomieliya\/#%D0%A4%D0%B0%D0%BA%D1%82%D0%BE%D1%80%D1%8B_%D1%80%D0%B8%D1%81%D0%BA%D0%B0_%D0%B2%D0%BE%D0%B7%D0%BD%D0%B8%D0%BA%D0%BD%D0%BE%D0%B2%D0%B5%D0%BD%D0%B8%D1%8F_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >Risk factors for the development of this disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/siringomieliya\/#%D0%94%D0%B8%D0%B0%D0%B3%D0%BD%D0%BE%D1%81%D1%82%D0%B8%D0%BA%D0%B0_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >Diagnosis of this disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/siringomieliya\/#%D0%9B%D0%B5%D1%87%D0%B5%D0%BD%D0%B8%D0%B5\" >Treatment<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/siringomieliya\/#%D0%A1%D0%BF%D0%B8%D1%81%D0%BE%D0%BA_%D0%BB%D0%B5%D0%BA%D0%B0%D1%80%D1%81%D1%82%D0%B2_%D0%BF%D1%80%D0%B8%D0%BC%D0%B5%D0%BD%D1%8F%D0%B5%D0%BC%D1%8B%D1%85_%D0%B4%D0%BB%D1%8F_%D0%BB%D0%B5%D1%87%D0%B5%D0%BD%D0%B8%D1%8F_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >List of medications used to treat this disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/siringomieliya\/#%D0%9C%D0%BE%D0%BD%D0%B8%D1%82%D0%BE%D1%80%D0%B8%D0%BD%D0%B3_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >Disease monitoring<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/siringomieliya\/#%D0%92%D0%BE%D0%B7%D1%80%D0%B0%D1%81%D1%82%D0%BD%D1%8B%D0%B5_%D0%BE%D1%81%D0%BE%D0%B1%D0%B5%D0%BD%D0%BD%D0%BE%D1%81%D1%82%D0%B8_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >Age-related features of the disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/siringomieliya\/#%D0%92%D0%BE%D0%BF%D1%80%D0%BE%D1%81%D1%8B_%D0%B8_%D0%BE%D1%82%D0%B2%D0%B5%D1%82%D1%8B\" >Questions and Answers<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"%D0%98%D1%81%D1%82%D0%BE%D1%80%D0%B8%D1%8F_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F_%D0%B8_%D0%B8%D0%BD%D1%82%D0%B5%D1%80%D0%B5%D1%81%D0%BD%D1%8B%D0%B5_%D0%B8%D1%81%D1%82%D0%BE%D1%80%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B8%D0%B5_%D1%84%D0%B0%D0%BA%D1%82%D1%8B\"><\/span>History of the disease and interesting historical facts<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The history of syringomyelia research dates back to the 19th century, when neurology first began to develop as a science. In 1863, British physician John Brown originally described the disease, highlighting its main symptoms and pathogenesis. Since then, researchers have continued to study the features of the pathological process, which has led to a deeper understanding of the mechanism of development and progression of the disease. An important step in the study of syringomyelia was the use of MRI in the 1980s, which made it possible to visualize changes in the spinal cord with high accuracy. Research in the field of genetics and molecular biology in recent years has opened up new perspectives for understanding syringomyelia and its pathogenetic mechanisms.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%AD%D0%BF%D0%B8%D0%B4%D0%B5%D0%BC%D0%B8%D0%BE%D0%BB%D0%BE%D0%B3%D0%B8%D1%8F\"><\/span>Epidemiology<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Syringomyelia is a rare condition, the true prevalence of which may vary depending on the population and region. According to various epidemiological studies, the incidence of syringomyelia is estimated to be approximately 8 to 18 cases per 100,000 population. Studies show that the disease is more common in people aged 20 to 40 years, although cases can be recorded in both children and elderly patients. Syringomyelia is diagnosed slightly more often in men than in women, which may indicate possible hormonal or genetic predisposition factors. An important aspect is that many patients may remain unaware of their condition, which makes it difficult to determine accurate statistics.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%93%D0%B5%D0%BD%D0%B5%D1%82%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B0%D1%8F_%D0%BF%D1%80%D0%B5%D0%B4%D1%80%D0%B0%D1%81%D0%BF%D0%BE%D0%BB%D0%BE%D0%B6%D0%B5%D0%BD%D0%BD%D0%BE%D1%81%D1%82%D1%8C_%D0%BA_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%BC%D1%83_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8E\"><\/span>Genetic predisposition to this disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Syringomyelia can be caused by both genetic and acquired factors. Current research indicates a high risk of developing syringomyelia in people with inherited connective tissue disorders such as Ehlers-Danlos syndrome and Marfan syndrome. Certain mutations in genes responsible for the development and maintenance of spinal cord structure can contribute to the formation of cysts. For example, abnormalities in genes associated with the extracellular matrix and neuronal plasticity have been associated with the development of syringomyelia. Genetic tests for predisposition to syringomyelia are still in development, but they can already be used to determine the risks in close relatives of patients.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%A4%D0%B0%D0%BA%D1%82%D0%BE%D1%80%D1%8B_%D1%80%D0%B8%D1%81%D0%BA%D0%B0_%D0%B2%D0%BE%D0%B7%D0%BD%D0%B8%D0%BA%D0%BD%D0%BE%D0%B2%D0%B5%D0%BD%D0%B8%D1%8F_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>Risk factors for the development of this disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>There are several risk factors that may contribute to the development of syringomyelia. The main ones include:<\/p>\n<ul>\n<li><strong>Genetic predisposition:<\/strong> presence of family cases of the disease.<\/li>\n<li><strong>Spinal cord injuries:<\/strong> acute injuries resulting from a fall or motor vehicle accident.<\/li>\n<li><strong>Chronic diseases of the spine:<\/strong> diseases that lead to changes in the anatomy of the spinal cord.<\/li>\n<li><strong>Neurological disorders:<\/strong> such as Arnold-Chiari malformation, which can contribute to the formation of cysts.<\/li>\n<li><strong>Professional risks:<\/strong> activities that involve increased stress on the spine.<\/li>\n<\/ul>\n<p>These factors can act either separately or in combination to contribute to the development of syringomyelia.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%94%D0%B8%D0%B0%D0%B3%D0%BD%D0%BE%D1%81%D1%82%D0%B8%D0%BA%D0%B0_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>Diagnosis of this disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Diagnosis of syringomyelia requires a comprehensive approach and may include several stages:<\/p>\n<ul>\n<li><strong>Main symptoms:<\/strong> loss of sensitivity, muscle weakness, pain syndromes, dystrophic changes in the skin.<\/li>\n<li><strong>Laboratory tests:<\/strong> general blood and urine tests, especially to rule out inflammatory or infectious processes.<\/li>\n<li><strong>Radiological examinations:<\/strong> Today, MRI is the most informative method for detecting the presence and size of cysts in the spinal cord.<\/li>\n<li><strong>Other types of diagnostics:<\/strong> Electrophysiological studies to assess nerve and muscle function.<\/li>\n<li><strong>Differential diagnosis:<\/strong> It is important to rule out other neurological diseases such as multiple sclerosis and myelopathy.<\/li>\n<\/ul>\n<p>In many cases, correct interpretation of examination results requires the participation of specialists in the fields of neurology and radiology.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%9B%D0%B5%D1%87%D0%B5%D0%BD%D0%B8%D0%B5\"><\/span>Treatment<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Treatment for syringomyelia is individual and depends on the severity of the disease and the symptoms present. It may include:<\/p><script data-noptimize=\"\" data-wpfc-render=\"false\">\nfpm_start( \"true\" );\n<\/script>\n\n<ul>\n<li><strong>General treatment:<\/strong> Physical therapy and exercises to maintain muscle and joint function.<\/li>\n<li><strong>Pharmacological treatment:<\/strong> pain relief drugs, antidepressants and anxiolytics to improve quality of life.<\/li>\n<li><strong>Surgical treatment:<\/strong> In cases of significant enlargement of cysts and the presence of neurological symptoms, surgical intervention may be indicated - drainage of cysts or decompression.<\/li>\n<li><strong>Other types of treatment:<\/strong> Alternative therapies such as acupuncture or manual therapy may be used as adjunctive measures.<\/li>\n<\/ul>\n<p>It is important to carry out treatment under the supervision of experienced specialists to avoid complications and improve the patient\u2019s quality of life.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%A1%D0%BF%D0%B8%D1%81%D0%BE%D0%BA_%D0%BB%D0%B5%D0%BA%D0%B0%D1%80%D1%81%D1%82%D0%B2_%D0%BF%D1%80%D0%B8%D0%BC%D0%B5%D0%BD%D1%8F%D0%B5%D0%BC%D1%8B%D1%85_%D0%B4%D0%BB%D1%8F_%D0%BB%D0%B5%D1%87%D0%B5%D0%BD%D0%B8%D1%8F_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>List of medications used to treat this disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Medicines used to treat syringomyelia may include:<\/p>\n<ul>\n<li>Nonsteroidal anti-inflammatory drugs (NSAIDs)<\/li>\n<li>Antidepressants (eg, amitriptyline)<\/li>\n<li>Analgesics (eg paracetamol or ibuprofen)<\/li>\n<li>Mucolytics (to improve blood circulation in the spinal cord)<\/li>\n<\/ul>\n<p>The choice of medications and dosage should be determined by a neurologist, taking into account the individual characteristics of the patient and the presence of concomitant diseases.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%9C%D0%BE%D0%BD%D0%B8%D1%82%D0%BE%D1%80%D0%B8%D0%BD%D0%B3_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>Disease monitoring<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Monitoring a patient with syringomyelia involves regular examinations and assessment of neurological function. Monitoring steps may include:<\/p>\n<ul>\n<li><strong>Neurological assessment:<\/strong> regular monitoring of symptoms and their dynamics.<\/li>\n<li><strong>Radiological control:<\/strong> Repeated MRIs at regular intervals to assess the size of cysts and changes in the spinal cord.<\/li>\n<li><strong>Forecast:<\/strong> With timely treatment, many patients can maintain their ability to work and remain viable, but cases of disability also occur.<\/li>\n<li><strong>Complications:<\/strong> may include progression of symptoms, need for surgery, and infection.<\/li>\n<\/ul>\n<p>It is important to remember that each case is unique and monitoring must be individualized.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%92%D0%BE%D0%B7%D1%80%D0%B0%D1%81%D1%82%D0%BD%D1%8B%D0%B5_%D0%BE%D1%81%D0%BE%D0%B1%D0%B5%D0%BD%D0%BD%D0%BE%D1%81%D1%82%D0%B8_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>Age-related features of the disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Syringomyelia can develop at any age, but its manifestations and behavior depend on the age group:<\/p>\n<ul>\n<li><strong>In children:<\/strong> The disease may manifest itself more often as neurological insufficiency, which requires special attention and early diagnosis.<\/li>\n<li><strong>In young people:<\/strong> Clinical symptoms may be more pronounced, often with severe pain or degenerative changes.<\/li>\n<li><strong>In older people:<\/strong> Symptoms may develop gradually, merging with natural aging, which sometimes makes diagnosis difficult.<\/li>\n<\/ul>\n<p>The patient&#039;s age should be taken into account when developing treatment and monitoring the condition.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%92%D0%BE%D0%BF%D1%80%D0%BE%D1%81%D1%8B_%D0%B8_%D0%BE%D1%82%D0%B2%D0%B5%D1%82%D1%8B\"><\/span>Questions and Answers<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<ul>\n<li><strong>What is syringomyelia?<\/strong> Syringomyelia is a disorder characterized by the formation of cysts in the spinal cord, which can cause neurological symptoms.<\/li>\n<li><strong>What are the main symptoms of syringomyelia?<\/strong> The main symptoms include loss of sensation, muscle weakness and pain.<\/li>\n<li><strong>How is syringomyelia diagnosed?<\/strong> The main diagnostic method is MRI, as well as assessment of neurological functions and laboratory tests.<\/li>\n<li><strong>How is syringomyelia treated?<\/strong> Treatment may include conservative measures, surgery, and medications to relieve symptoms.<\/li>\n<li><strong>What is the prognosis for syringomyelia?<\/strong> The prognosis depends on the individual characteristics of the patient, but with timely treatment it is possible to maintain working capacity and improve quality of life.<\/li>\n<\/ul>\n<div class=\"fpm_end\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Syringomyelia is a neurological disorder characterized by the formation of spinal fluid-filled cysts (syringes) in the spinal cord. These cysts can gradually enlarge<\/p>","protected":false},"author":1,"featured_media":23149,"comment_status":"open","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[298],"tags":[],"class_list":["post-13012","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medlibrary"],"_links":{"self":[{"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/posts\/13012","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/comments?post=13012"}],"version-history":[{"count":1,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/posts\/13012\/revisions"}],"predecessor-version":[{"id":13909,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/posts\/13012\/revisions\/13909"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/media\/23149"}],"wp:attachment":[{"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/media?parent=13012"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/categories?post=13012"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/tags?post=13012"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}