{"id":12957,"date":"2024-08-23T07:36:58","date_gmt":"2024-08-23T05:36:58","guid":{"rendered":"https:\/\/valintermed.com\/?p=12957"},"modified":"2024-08-23T07:36:58","modified_gmt":"2024-08-23T05:36:58","slug":"sindrom-sapho","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/sindrom-sapho\/","title":{"rendered":"SAPHO syndrome"},"content":{"rendered":"
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SAPHO syndrome (sandwich syndrome) is a rare disorder characterized by a combination of arthritis, skin manifestations, and systemic organ involvement in the context of hyperostotic changes. This syndrome is the result of a combination of various pathological processes leading to systemic disturbances, including joint destruction and inflammation. Although the exact mechanism of the disease remains unclear, it is assumed that both genetic and exogenous factors affecting the immune system and inflammatory processes play a role. The first signs of the syndrome can vary from relatively mild to severe symptoms, which complicates its early diagnosis and leads to significant clinical consequences.<\/p>\n

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