{"id":12847,"date":"2024-09-08T12:42:29","date_gmt":"2024-09-08T10:42:29","guid":{"rendered":"https:\/\/valintermed.com\/?p=12847"},"modified":"2024-09-08T12:42:29","modified_gmt":"2024-09-08T10:42:29","slug":"anevrizma-sinusa-valsalvy","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/sinus-valvular-aneurysm\/","title":{"rendered":"Aneurysm of the sinus of Valsalva"},"content":{"rendered":"<div class=\"fpm_start\"><\/div>\n<p>Aneurysm of the sinus of Valsalva is a pathological dilation of the sinus of Valsalva, located in the aortic root area. This condition can be both congenital and acquired, and is characterized by a change in the wall of the vascular structure, which can lead to serious clinical consequences. Disturbances in the structure of the aneurysm can cause various complications, including compression of surrounding anatomical structures and the development of cardiovascular insufficiency. Depending on the size and location of the aneurysm, clinical manifestations can vary from asymptomatic to acute circulatory failure. Timely diagnosis and treatment of sinus of Valsalva aneurysm are crucial to reduce the risk of serious complications.<\/p>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_86 counter-flat ez-toc-counter ez-toc-light-blue ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Content<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" 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href=\"https:\/\/valintermed.com\/en\/medlibrary\/sinus-valvular-aneurysm\/#%D0%98%D1%81%D1%82%D0%BE%D1%80%D0%B8%D1%8F_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F_%D0%B8_%D0%B8%D0%BD%D1%82%D0%B5%D1%80%D0%B5%D1%81%D0%BD%D1%8B%D0%B5_%D0%B8%D1%81%D1%82%D0%BE%D1%80%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B8%D0%B5_%D1%84%D0%B0%D0%BA%D1%82%D1%8B\" >History of the disease and interesting historical facts<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/sinus-valvular-aneurysm\/#%D0%AD%D0%BF%D0%B8%D0%B4%D0%B5%D0%BC%D0%B8%D0%BE%D0%BB%D0%BE%D0%B3%D0%B8%D1%8F\" >Epidemiology<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/sinus-valvular-aneurysm\/#%D0%93%D0%B5%D0%BD%D0%B5%D1%82%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B0%D1%8F_%D0%BF%D1%80%D0%B5%D0%B4%D1%80%D0%B0%D1%81%D0%BF%D0%BE%D0%BB%D0%BE%D0%B6%D0%B5%D0%BD%D0%BD%D0%BE%D1%81%D1%82%D1%8C_%D0%BA_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%BC%D1%83_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8E\" >Genetic predisposition to this disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/sinus-valvular-aneurysm\/#%D0%A4%D0%B0%D0%BA%D1%82%D0%BE%D1%80%D1%8B_%D1%80%D0%B8%D1%81%D0%BA%D0%B0_%D0%B2%D0%BE%D0%B7%D0%BD%D0%B8%D0%BA%D0%BD%D0%BE%D0%B2%D0%B5%D0%BD%D0%B8%D1%8F_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >Risk factors for the development of this disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/sinus-valvular-aneurysm\/#%D0%94%D0%B8%D0%B0%D0%B3%D0%BD%D0%BE%D1%81%D1%82%D0%B8%D0%BA%D0%B0_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >Diagnosis of this disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/sinus-valvular-aneurysm\/#%D0%9B%D0%B5%D1%87%D0%B5%D0%BD%D0%B8%D0%B5\" >Treatment<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/sinus-valvular-aneurysm\/#%D0%A1%D0%BF%D0%B8%D1%81%D0%BE%D0%BA_%D0%BB%D0%B5%D0%BA%D0%B0%D1%80%D1%81%D1%82%D0%B2_%D0%BF%D1%80%D0%B8%D0%BC%D0%B5%D0%BD%D1%8F%D0%B5%D0%BC%D1%8B%D1%85_%D0%B4%D0%BB%D1%8F_%D0%BB%D0%B5%D1%87%D0%B5%D0%BD%D0%B8%D1%8F_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >List of drugs used to treat this disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/sinus-valvular-aneurysm\/#%D0%9C%D0%BE%D0%BD%D0%B8%D1%82%D0%BE%D1%80%D0%B8%D0%BD%D0%B3_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >Disease monitoring<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/sinus-valvular-aneurysm\/#%D0%92%D0%BE%D0%B7%D1%80%D0%B0%D1%81%D1%82%D0%BD%D1%8B%D0%B5_%D0%BE%D1%81%D0%BE%D0%B1%D0%B5%D0%BD%D0%BD%D0%BE%D1%81%D1%82%D0%B8_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >Age-related features of the disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/sinus-valvular-aneurysm\/#%D0%92%D0%BE%D0%BF%D1%80%D0%BE%D1%81%D1%8B_%D0%B8_%D0%BE%D1%82%D0%B2%D0%B5%D1%82%D1%8B\" >Questions and Answers<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"%D0%98%D1%81%D1%82%D0%BE%D1%80%D0%B8%D1%8F_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F_%D0%B8_%D0%B8%D0%BD%D1%82%D0%B5%D1%80%D0%B5%D1%81%D0%BD%D1%8B%D0%B5_%D0%B8%D1%81%D1%82%D0%BE%D1%80%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B8%D0%B5_%D1%84%D0%B0%D0%BA%D1%82%D1%8B\"><\/span>History of the disease and interesting historical facts<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Historically, sinus of Valsalva aneurysms were first described in the literature in the 19th century, but a true understanding of the condition only became possible with the advancement of medical imaging and cardiovascular surgery. The study of sinus of Valsalva aneurysms was pioneered by scientists such as Valsalva, after whom the anatomical formation was named. In the 1970s and 80s, with the development of echocardiography, cases of this pathology became more common. Important steps in the treatment of the aneurysm were made with the introduction of modern surgical techniques and materials, which contributed to improved patient outcomes. Interestingly, sinus of Valsalva aneurysms often occur in young people, which has sparked debate among scientists about the genetic and environmental factors that contribute to the development of this condition.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%AD%D0%BF%D0%B8%D0%B4%D0%B5%D0%BC%D0%B8%D0%BE%D0%BB%D0%BE%D0%B3%D0%B8%D1%8F\"><\/span>Epidemiology<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Sinus of Valsalva aneurysm is a relatively rare condition, but statistics show that its occurrence is between 0.1% and 0.5% among all cardiac anomalies. The condition occurs in men and women with almost equal frequency, but the latter is at increased risk due to the high probability of comorbidities. Some studies have found that sinus of Valsalva aneurysm may be more common in certain ethnic groups, as genetic predisposition may influence the incidence of the disease. Further research is needed to gain a more complete understanding of the factors contributing to the development of aneurysms and their prevalence in the population.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%93%D0%B5%D0%BD%D0%B5%D1%82%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B0%D1%8F_%D0%BF%D1%80%D0%B5%D0%B4%D1%80%D0%B0%D1%81%D0%BF%D0%BE%D0%BB%D0%BE%D0%B6%D0%B5%D0%BD%D0%BD%D0%BE%D1%81%D1%82%D1%8C_%D0%BA_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%BC%D1%83_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8E\"><\/span>Genetic predisposition to this disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Genetic predisposition to sinus of Valsalva aneurysm is still a subject of active research. Various scientific papers indicate the possibility of a hereditary predisposition to stenosis and aneurysm of the sinus of Valsalva in people with certain genetic disorders. The study of mutations associated with collagenoses and elastoses has shown that genes responsible for collagen synthesis (for example, COL3A1) may be involved in the pathogenesis of this disease. Studies have also revealed a relationship between aneurysm formation and Marfan syndrome, which is characterized by systemic changes in connective tissue. However, additional prospective studies are needed to prove these relationships.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%A4%D0%B0%D0%BA%D1%82%D0%BE%D1%80%D1%8B_%D1%80%D0%B8%D1%81%D0%BA%D0%B0_%D0%B2%D0%BE%D0%B7%D0%BD%D0%B8%D0%BA%D0%BD%D0%BE%D0%B2%D0%B5%D0%BD%D0%B8%D1%8F_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>Risk factors for the development of this disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Risk factors for sinus of Valsalva aneurysm can be both exogenous and endogenous. The main risk factors include:<\/p>\n<ul>\n<li>Age \u2013 a higher predisposition is observed in young people aged 20 to 40 years.<\/li>\n<li>Heredity \u2013 a family history of aneurysms increases the risk of developing the disease.<\/li>\n<li>Systemic connective tissue diseases such as Marfan syndrome and Ehlers-Danlos syndrome.<\/li>\n<li>Hypertension \u2013 high blood pressure creates additional stress on the walls of blood vessels.<\/li>\n<li>Infectious diseases \u2013 some infections can increase the risk of damage to the vessel wall and the development of an aneurysm.<\/li>\n<\/ul>\n<p>Also important is the influence of lifestyle factors such as smoking and obesity, which can contribute to the development of cardiovascular disease and, as a result, aneurysm.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%94%D0%B8%D0%B0%D0%B3%D0%BD%D0%BE%D1%81%D1%82%D0%B8%D0%BA%D0%B0_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>Diagnosis of this disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The main symptoms of a sinus of Valsalva aneurysm may include:<\/p>\n<ul>\n<li>Chest pain that may radiate to the neck, shoulders, or back.<\/li>\n<li>Shortness of breath, rapid heartbeat.<\/li>\n<li>Dizziness and fainting, especially during physical exertion.<\/li>\n<li>Symptoms of heart failure as the disease progresses.<\/li>\n<\/ul>\n<p>Various methods are used to diagnose aneurysm of the sinus of Valsalva:<\/p>\n<ul>\n<li>Laboratory tests \u2013 complete blood count, coagulation parameters.<\/li>\n<li>Radiological examinations \u2013 echocardiography, magnetic resonance imaging (MRI), computed tomography (CT).<\/li>\n<li>Angiography is an invasive method that allows assessing the degree of vascular pathology.<\/li>\n<li>Other types of diagnostics, including ECG monitoring.<\/li>\n<\/ul>\n<p>Differential diagnosis must be made with other cardiac diseases such as aortic stenosis, myocarditis or infective endocarditis, which significantly affects the choice of treatment method.<\/p><script data-noptimize=\"\" data-wpfc-render=\"false\">\nfpm_start( \"true\" );\n<\/script>\n\n<h2><span class=\"ez-toc-section\" id=\"%D0%9B%D0%B5%D1%87%D0%B5%D0%BD%D0%B8%D0%B5\"><\/span>Treatment<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Treatment for a sinus of Valsalva aneurysm depends on the size, symptoms, and complications. The main approaches to treatment include:<\/p>\n<ul>\n<li>General treatment is supportive therapy to manage the symptoms of cardiovascular failure.<\/li>\n<li>Pharmacological treatment \u2013 beta-blockers may be prescribed to control heart rhythm and reduce the workload on the heart.<\/li>\n<li>Surgical treatment \u2013 in case of large aneurysms or complications, surgery is indicated, including vascular prosthetics or reconstruction.<\/li>\n<li>Other treatments may include minimally invasive techniques such as endovascular intervention.<\/li>\n<\/ul>\n<p>Each case of aneurysm requires an individual approach based on the clinical picture and examination results.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%A1%D0%BF%D0%B8%D1%81%D0%BE%D0%BA_%D0%BB%D0%B5%D0%BA%D0%B0%D1%80%D1%81%D1%82%D0%B2_%D0%BF%D1%80%D0%B8%D0%BC%D0%B5%D0%BD%D1%8F%D0%B5%D0%BC%D1%8B%D1%85_%D0%B4%D0%BB%D1%8F_%D0%BB%D0%B5%D1%87%D0%B5%D0%BD%D0%B8%D1%8F_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>List of drugs used to treat this disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The main medications used to treat sinus of Valsalva aneurysm may include:<\/p>\n<ul>\n<li>Beta-blockers (eg, metoprolol, atenolol) to control heart rate.<\/li>\n<li>Antihypertensive drugs for blood pressure control.<\/li>\n<li>Anticoagulants to prevent thrombus formation in the presence of associated complications.<\/li>\n<li>Diuretics to reduce swelling and reduce the overall load on the cardiovascular system.<\/li>\n<li>Vasodilators to improve blood circulation.<\/li>\n<\/ul>\n<p>These drugs are prescribed depending on the clinical picture and other concomitant diseases.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%9C%D0%BE%D0%BD%D0%B8%D1%82%D0%BE%D1%80%D0%B8%D0%BD%D0%B3_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>Disease monitoring<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Monitoring the patient&#039;s condition with a sinus of Valsalva aneurysm is a key element in managing the disease. Control steps include:<\/p>\n<ul>\n<li>Regular echocardiographic studies to assess the size and dynamics of the aneurysm.<\/li>\n<li>Periodic checks for new symptoms or complications.<\/li>\n<li>Evaluation and correction of treatment algorithms based on the patient&#039;s condition.<\/li>\n<\/ul>\n<p>Prognosis depends on the size and level of intervention, most cases with early diagnosis and proper treatment have a favorable outcome. Complications may include rupture of the aneurysm, which requires emergency medical intervention.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%92%D0%BE%D0%B7%D1%80%D0%B0%D1%81%D1%82%D0%BD%D1%8B%D0%B5_%D0%BE%D1%81%D0%BE%D0%B1%D0%B5%D0%BD%D0%BD%D0%BE%D1%81%D1%82%D0%B8_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>Age-related features of the disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Aneurysm of the sinus of Valsalva can occur in different age groups, but there are certain patterns:<\/p>\n<ul>\n<li>In young people, aneurysms are often congenital or associated with genetic disorders.<\/li>\n<li>In middle age, diseases are more likely to arise as a result of degenerative changes over time, such as atherosclerosis.<\/li>\n<li>Elderly patients have a high risk of complications and ruptures due to the deterioration of the general condition of the vessels and the presence of concomitant diseases.<\/li>\n<\/ul>\n<p>Thus, the approach to diagnosis and treatment of aneurysm should vary depending on the patient&#039;s age category.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%92%D0%BE%D0%BF%D1%80%D0%BE%D1%81%D1%8B_%D0%B8_%D0%BE%D1%82%D0%B2%D0%B5%D1%82%D1%8B\"><\/span>Questions and Answers<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<ul>\n<li><strong>What are the main symptoms of a sinus of Valsalva aneurysm?<\/strong> Symptoms may include chest pain, shortness of breath, dizziness, and fainting, especially with physical activity.<\/li>\n<li><strong>What diagnostic methods are used to detect aneurysms?<\/strong> Diagnostics include echocardiography, MRI, CT, and angiography for a detailed assessment of the condition of the vessels.<\/li>\n<li><strong>How is sinus of Valsalva aneurysm treated?<\/strong> Treatment can be conservative, using medications, or surgical, depending on the size of the aneurysm and the presence of symptoms.<\/li>\n<li><strong>What is the prognosis for patients with sinus of Valsalva aneurysm?<\/strong> The prognosis depends on the size and condition of the aneurysm; with early diagnosis and treatment, most patients have a good outcome.<\/li>\n<li><strong>What is the role of genetics in the development of sinus of Valsalva aneurysm?<\/strong> Genetic factors, including the presence of inherited connective tissue disorders, may increase the risk of developing an aneurysm.<\/li>\n<\/ul>\n<div class=\"fpm_end\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Aneurysm of the sinus of Valsalva is an abnormal dilation of the sinus of Valsalva, located in the region of the aortic root. This condition can be either congenital,<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[298],"tags":[],"class_list":["post-12847","post","type-post","status-publish","format-standard","hentry","category-medlibrary"],"_links":{"self":[{"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/posts\/12847","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/comments?post=12847"}],"version-history":[{"count":1,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/posts\/12847\/revisions"}],"predecessor-version":[{"id":14102,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/posts\/12847\/revisions\/14102"}],"wp:attachment":[{"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/media?parent=12847"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/categories?post=12847"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/tags?post=12847"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}