{"id":12816,"date":"2024-09-17T21:46:42","date_gmt":"2024-09-17T19:46:42","guid":{"rendered":"https:\/\/valintermed.com\/?p=12816"},"modified":"2024-09-22T10:56:50","modified_gmt":"2024-09-22T08:56:50","slug":"rinofima","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/rinofima\/","title":{"rendered":"Rhinophyma"},"content":{"rendered":"<div class=\"fpm_start\"><\/div>\n<p>Rhinophyma is a chronic skin condition that causes thickening and deformation of the tissues of the nose. It is a form of rosacea and is most common in middle-aged and older men. Rhinophyma is characterized by the formation of nodular lesions, changes in skin color, and, as a rule, a noticeable enlargement of the nose. These changes can be not only a physical but also a psychological burden for the patient, leading to social and emotional problems. Rhinophyma occurs as a result of inflammation and damage to the vascular and connective tissue structure of the skin, which is caused by a long-term inflammatory process.<\/p>\n<div style=\"width: 1280px;\" class=\"wp-video\"><video class=\"wp-video-shortcode\" id=\"video-12816-1\" width=\"1280\" height=\"720\" preload=\"metadata\" controls=\"controls\"><source type=\"video\/mp4\" src=\"https:\/\/valintermed.com\/wp-content\/uploads\/2024\/09\/rinofima-eto-hronicheskoe-zabolevanie-kozhi-kotor-720p-240922-1.mp4?_=1\" \/><a href=\"https:\/\/valintermed.com\/wp-content\/uploads\/2024\/09\/rinofima-eto-hronicheskoe-zabolevanie-kozhi-kotor-720p-240922-1.mp4\">https:\/\/valintermed.com\/wp-content\/uploads\/2024\/09\/rinofima-eto-hronicheskoe-zabolevanie-kozhi-kotor-720p-240922-1.mp4<\/a><\/video><\/div>\n<hr \/>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_86 counter-flat ez-toc-counter ez-toc-light-blue ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Content<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 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>Epidemiology<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/rinofima\/#%D0%93%D0%B5%D0%BD%D0%B5%D1%82%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B0%D1%8F_%D0%BF%D1%80%D0%B5%D0%B4%D1%80%D0%B0%D1%81%D0%BF%D0%BE%D0%BB%D0%BE%D0%B6%D0%B5%D0%BD%D0%BD%D0%BE%D1%81%D1%82%D1%8C_%D0%BA_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%BC%D1%83_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8E\" >Genetic predisposition to this disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/rinofima\/#%D0%A4%D0%B0%D0%BA%D1%82%D0%BE%D1%80%D1%8B_%D1%80%D0%B8%D1%81%D0%BA%D0%B0_%D0%B2%D0%BE%D0%B7%D0%BD%D0%B8%D0%BA%D0%BD%D0%BE%D0%B2%D0%B5%D0%BD%D0%B8%D1%8F_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >Risk factors for the development of this disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/rinofima\/#%D0%94%D0%B8%D0%B0%D0%B3%D0%BD%D0%BE%D1%81%D1%82%D0%B8%D0%BA%D0%B0_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >Diagnosis of this disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/rinofima\/#%D0%9B%D0%B5%D1%87%D0%B5%D0%BD%D0%B8%D0%B5\" >Treatment<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/rinofima\/#%D0%A1%D0%BF%D0%B8%D1%81%D0%BE%D0%BA_%D0%BB%D0%B5%D0%BA%D0%B0%D1%80%D1%81%D1%82%D0%B2_%D0%BF%D1%80%D0%B8%D0%BC%D0%B5%D0%BD%D1%8F%D0%B5%D0%BC%D1%8B%D1%85_%D0%B4%D0%BB%D1%8F_%D0%BB%D0%B5%D1%87%D0%B5%D0%BD%D0%B8%D1%8F_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >List of medications used to treat this disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/rinofima\/#%D0%9C%D0%BE%D0%BD%D0%B8%D1%82%D0%BE%D1%80%D0%B8%D0%BD%D0%B3_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >Disease monitoring<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/rinofima\/#%D0%92%D0%BE%D0%B7%D1%80%D0%B0%D1%81%D1%82%D0%BD%D1%8B%D0%B5_%D0%BE%D1%81%D0%BE%D0%B1%D0%B5%D0%BD%D0%BD%D0%BE%D1%81%D1%82%D0%B8_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >Age-related features of the disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/rinofima\/#%D0%92%D0%BE%D0%BF%D1%80%D0%BE%D1%81%D1%8B_%D0%B8_%D0%BE%D1%82%D0%B2%D0%B5%D1%82%D1%8B\" >Questions and Answers<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"%D0%98%D1%81%D1%82%D0%BE%D1%80%D0%B8%D1%8F_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F_%D0%B8_%D0%B8%D0%BD%D1%82%D0%B5%D1%80%D0%B5%D1%81%D0%BD%D1%8B%D0%B5_%D0%B8%D1%81%D1%82%D0%BE%D1%80%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B8%D0%B5_%D1%84%D0%B0%D0%BA%D1%82%D1%8B\"><\/span>History of the disease and interesting historical facts<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Rhinophyma has been known since ancient times and was described by Hippocrates. However, the first scientific description of this pathology was presented in the 17th century, when the Italian doctor A. Caprini identified rhinophyma as an independent disease. At the beginning of the 20th century, the disease again attracted the attention of doctors with the development of dermatology and cosmetic surgery. At that time, various treatment methods were developed, such as cryotherapy and electrocoagulation. Interesting fact: in the 19th century, rhinophyma was called the &quot;nose of alcoholics&quot;, since its manifestations were often found in people who abused alcohol. Nowadays, the attitude towards this disease has changed, and it is considered a multifactorial dermatological dysfunction.<\/p>\n<div style=\"width: 1280px;\" class=\"wp-video\"><video class=\"wp-video-shortcode\" id=\"video-12816-2\" width=\"1280\" height=\"720\" preload=\"metadata\" controls=\"controls\"><source type=\"video\/mp4\" src=\"https:\/\/valintermed.com\/wp-content\/uploads\/2024\/09\/rinofima-eto-hronicheskoe-zabolevanie-kozhi-kotor-720p-240922.mp4?_=2\" \/><a href=\"https:\/\/valintermed.com\/wp-content\/uploads\/2024\/09\/rinofima-eto-hronicheskoe-zabolevanie-kozhi-kotor-720p-240922.mp4\">https:\/\/valintermed.com\/wp-content\/uploads\/2024\/09\/rinofima-eto-hronicheskoe-zabolevanie-kozhi-kotor-720p-240922.mp4<\/a><\/video><\/div>\n<h2><span class=\"ez-toc-section\" id=\"%D0%AD%D0%BF%D0%B8%D0%B4%D0%B5%D0%BC%D0%B8%D0%BE%D0%BB%D0%BE%D0%B3%D0%B8%D1%8F\"><\/span>Epidemiology<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The epidemiology of rhinophyma has its own characteristics. According to various studies, the prevalence of rhinophyma among patients with rosacea is about 5-10%. This disease is more common in men (80% cases) than in women. In addition, the average age of patients with rhinophyma varies from 50 to 70 years. It is important that the most severe forms of the disease occur in people with pronounced red skin and blond hair, which may be due to their genetic predisposition.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%93%D0%B5%D0%BD%D0%B5%D1%82%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B0%D1%8F_%D0%BF%D1%80%D0%B5%D0%B4%D1%80%D0%B0%D1%81%D0%BF%D0%BE%D0%BB%D0%BE%D0%B6%D0%B5%D0%BD%D0%BD%D0%BE%D1%81%D1%82%D1%8C_%D0%BA_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%BC%D1%83_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8E\"><\/span>Genetic predisposition to this disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>At present, there is an opinion that rhinophyma may have a genetic predisposition, although the exact mechanisms have not been fully established. Studies show that patients with rhinophyma have changes in the expression of a number of genes involved in the regulation of inflammatory processes. In particular, changes in genes associated with the inflammatory response and vasoregulation. One of these genes is the gene encoding VEGF (vascular endothelial growth factor). The hypothesis of a familial predisposition requires further research, but the presence of such a predisposition may be an important aspect of diagnosis and treatment.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%A4%D0%B0%D0%BA%D1%82%D0%BE%D1%80%D1%8B_%D1%80%D0%B8%D1%81%D0%BA%D0%B0_%D0%B2%D0%BE%D0%B7%D0%BD%D0%B8%D0%BA%D0%BD%D0%BE%D0%B2%D0%B5%D0%BD%D0%B8%D1%8F_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>Risk factors for the development of this disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>There are several risk factors that may contribute to the development of rhinophyma, including:<\/p>\n<ul>\n<li>Genetic predisposition<\/li>\n<li>Long-term exposure to sunlight<\/li>\n<li>Alcohol abuse<\/li>\n<li>The influence of high temperatures and thermal effects<\/li>\n<li>Stress and emotional tension<\/li>\n<li>Chronic skin diseases<\/li>\n<\/ul>\n<p>These factors may serve as triggers for exacerbation of rhinophyma and should be considered when making a diagnosis and developing a treatment plan.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%94%D0%B8%D0%B0%D0%B3%D0%BD%D0%BE%D1%81%D1%82%D0%B8%D0%BA%D0%B0_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>Diagnosis of this disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Diagnosis of rhinophyma is based on clinical examination and analysis of anamnestic data. The main symptoms include:<\/p>\n<ul>\n<li>Thickening of the skin of the nose<\/li>\n<li>The appearance of tumor-like formations<\/li>\n<li>Skin color changes (red, brown, or yellowish patches)<\/li>\n<li>Rock changes, loss of aesthetic appearance<\/li>\n<\/ul>\n<p>Laboratory tests are usually of little use in diagnosing rhinophyma, but may be used to exclude other conditions. Radiological examinations are not routine for this pathology, except in cases where it is necessary to exclude more serious changes in surrounding structures. Differential diagnosis includes such diseases as nasal tumors, keratoacanthoma, and other forms of rosacea, which may have a similar clinical picture.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%9B%D0%B5%D1%87%D0%B5%D0%BD%D0%B8%D0%B5\"><\/span>Treatment<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Treatment of rhinophyma can be multifaceted and should be individualized for each patient. In general, treatment includes:<\/p><script data-noptimize=\"\" data-wpfc-render=\"false\">\nfpm_start( \"true\" );\n<\/script>\n\n<ul>\n<li>Pharmacological treatment - anti-inflammatory and antibiotic drugs.<\/li>\n<li>Surgical treatments include excision of excess tissue, laser procedures and dermabrasion.<\/li>\n<li>Cosmetic procedures are the use of special restorative products to improve appearance.<\/li>\n<li>Long-term treatment plan - lifestyle correction and changes in routine.<\/li>\n<\/ul>\n<p>In the early stages, conservative therapy may be sufficient, however, in more advanced cases, surgical methods may be the only option for solving the problem.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%A1%D0%BF%D0%B8%D1%81%D0%BE%D0%BA_%D0%BB%D0%B5%D0%BA%D0%B0%D1%80%D1%81%D1%82%D0%B2_%D0%BF%D1%80%D0%B8%D0%BC%D0%B5%D0%BD%D1%8F%D0%B5%D0%BC%D1%8B%D1%85_%D0%B4%D0%BB%D1%8F_%D0%BB%D0%B5%D1%87%D0%B5%D0%BD%D0%B8%D1%8F_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>List of medications used to treat this disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Doctors may have the following medications in their arsenal for treating rhinophyma:<\/p>\n<ul>\n<li>Doxycycline<\/li>\n<li>Tetracycline<\/li>\n<li>Metronidazole<\/li>\n<li>Isotretinoin<\/li>\n<li>Corticosteroids<\/li>\n<\/ul>\n<p>Pharmacological therapy may include topical agents, creams and gels for local application.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%9C%D0%BE%D0%BD%D0%B8%D1%82%D0%BE%D1%80%D0%B8%D0%BD%D0%B3_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>Disease monitoring<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Regular monitoring of the patient&#039;s condition is important to assess the dynamics of the disease and adjust treatment. The prognosis for people with rhinophyma depends on the stage of the disease and the treatment used. In most cases, with early treatment and proper therapy, good results can be achieved. Complications may include infectious lesions and psychological disorders associated with aesthetic deformation.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%92%D0%BE%D0%B7%D1%80%D0%B0%D1%81%D1%82%D0%BD%D1%8B%D0%B5_%D0%BE%D1%81%D0%BE%D0%B1%D0%B5%D0%BD%D0%BD%D0%BE%D1%81%D1%82%D0%B8_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>Age-related features of the disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Rhinophyma can occur in different age groups, but is most common in middle-aged and older men. In younger people, the disease usually has less pronounced symptoms, while in older men, rhinophyma can manifest itself more aggressively and lead to significant cosmetic defects.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%92%D0%BE%D0%BF%D1%80%D0%BE%D1%81%D1%8B_%D0%B8_%D0%BE%D1%82%D0%B2%D0%B5%D1%82%D1%8B\"><\/span>Questions and Answers<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<ul>\n<li><strong>What is rhinophyma?<\/strong> Rhinophyma is a chronic skin condition characterized by thickening and changes in the appearance of the nose.<\/li>\n<li><strong>Who is more likely to suffer from rhinophyma?<\/strong> Rhinophyma most often occurs in middle-aged and older men who are predisposed to rosacea.<\/li>\n<li><strong>How to diagnose rhinophyma?<\/strong> Diagnosis is based on visual examination and assessment of symptoms, as well as differential diagnosis.<\/li>\n<li><strong>How is rhinophyma treated?<\/strong> Treatment may include medication, cosmetic procedures, and surgery.<\/li>\n<li><strong>What is the prognosis for rhinophyma?<\/strong> The prognosis depends on the stage of the disease and the chosen method of treatment; good results can be achieved with early treatment.<\/li>\n<\/ul>\n<div class=\"fpm_end\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Rhinophyma is a chronic skin condition that causes thickening and deformation of the tissues of the nose. This condition is a form of rosacea.<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[298],"tags":[],"class_list":["post-12816","post","type-post","status-publish","format-standard","hentry","category-medlibrary"],"_links":{"self":[{"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/posts\/12816","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/comments?post=12816"}],"version-history":[{"count":3,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/posts\/12816\/revisions"}],"predecessor-version":[{"id":14222,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/posts\/12816\/revisions\/14222"}],"wp:attachment":[{"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/media?parent=12816"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/categories?post=12816"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/tags?post=12816"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}