{"id":12642,"date":"2024-10-11T18:14:01","date_gmt":"2024-10-11T16:14:01","guid":{"rendered":"https:\/\/valintermed.com\/?p=12642"},"modified":"2024-10-11T18:14:01","modified_gmt":"2024-10-11T16:14:01","slug":"psevdogipoaldosteronizm-2-tipa","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/pseudogipoaldosteronizm-2-tipa\/","title":{"rendered":"Pseudohypoaldosteronism type 2"},"content":{"rendered":"
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Pseudohypoaldosteronism type 2 (PHA2) is a rare inherited disorder characterized by persistent hyperkalemia and metabolic acidosis syndrome with normal or elevated serum aldosterone levels. This condition is due to dysfunction of sodium-magnesium-adenosine triphosphatase (Na+\/K+-ATPase) in the renal tubules, which leads to impaired sodium and potassium reabsorption, resulting in hypoeclampsia, hypervolemia, and hypertension. Despite the presence of aldosterone in the blood, the symptoms of pseudohypoaldosteronism are due to the ineffectiveness of this hormone in the kidneys, which explains the pronounced clinical manifestations of this disease.<\/p>\n

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