{"id":12541,"date":"2024-10-11T19:54:13","date_gmt":"2024-10-11T17:54:13","guid":{"rendered":"https:\/\/valintermed.com\/?p=12541"},"modified":"2024-10-11T19:54:13","modified_gmt":"2024-10-11T17:54:13","slug":"pervichnyy-lokalizovannyy-kozhnyy-amiloidoz","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/primary-localized-cutaneous-amyloidosis\/","title":{"rendered":"Primary localized cutaneous amyloidosis"},"content":{"rendered":"
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Primary localized cutaneous amyloidosis (PLCA) is a rare skin disorder characterized by the deposition of amyloid proteins in the dermis and epidermis. These abnormally structured proteins are formed from abnormally folded fibrillar proteins and result in the formation of localized amyloid plaques. The most commonly affected areas of the skin are the upper back, chest, face, and extremities. The disease appears as itchy, painless, firm plaques that may be yellowish-brown in color. PLCA is usually benign and does not cause systemic manifestations, but can have a significant impact on the patient's quality of life due to the unsightly appearance of the skin.<\/p>\n

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