{"id":12450,"date":"2024-10-11T21:19:33","date_gmt":"2024-10-11T19:19:33","guid":{"rendered":"https:\/\/valintermed.com\/?p=12450"},"modified":"2024-10-11T21:19:33","modified_gmt":"2024-10-11T19:19:33","slug":"defitsit-psevdoholinesterazy","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/pseudocholinesterase-deficiency\/","title":{"rendered":"Pseudocholinesterase deficiency"},"content":{"rendered":"
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Pseudocholinesterase deficiency is a genetic disorder associated with insufficient activity of the enzyme pseudocholinesterase, which plays a key role in the metabolism of certain drugs and neurotransmitters such as acetylcholine. Pseudocholinesterase, synthesized by the liver, is involved in the breakdown of acetylcholine in synapses, which is critical for maintaining normal nervous system function. Deficiency of this enzyme can lead to prolonged action of muscle relaxants and anesthetics, causing serious consequences such as prolonged muscle weakness and respiratory distress during general anesthesia. In this context, timely diagnosis and correct treatment are extremely important to prevent complications.<\/p>\n

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