{"id":12438,"date":"2024-10-11T21:37:54","date_gmt":"2024-10-11T19:37:54","guid":{"rendered":"https:\/\/valintermed.com\/?p=12438"},"modified":"2024-10-11T21:37:54","modified_gmt":"2024-10-11T19:37:54","slug":"defitsit-belka-s","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/belka-s-deficit\/","title":{"rendered":"Protein S deficiency"},"content":{"rendered":"
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Protein S deficiency is a rare but potentially serious disorder associated with an increased risk of thrombotic events. Protein S is a plasma glycoprotein that plays a key role in maintaining hemostasis by promoting the breakdown of prothrombin and inhibiting the activity of coagulation factors such as factor V and factor VIII. Protein S deficiency can be either hereditary or acquired, which affects its clinical presentation and treatment approaches. Clinical manifestations include recurrent venous thromboembolism and the risk of thrombotic events, particularly in the deep veins. There is also evidence that the risk of venous thromboembolism is increased during pregnancy and after surgery.<\/p>\n

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