{"id":12423,"date":"2024-10-11T21:53:19","date_gmt":"2024-10-11T19:53:19","guid":{"rendered":"https:\/\/valintermed.com\/?p=12423"},"modified":"2024-10-11T21:53:19","modified_gmt":"2024-10-11T19:53:19","slug":"bolezn-pelitseusa-mertsbahera","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/pelvic-pain-disease\/","title":{"rendered":"Pelizaeus-Merzbacher disease"},"content":{"rendered":"
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Pelizaeus-Merzbacher disease (PMD) is a rare inherited disorder that belongs to the group of myelinopathies. This disease is caused by defects in the formation of myelin, which is an insulating sheath covering nerve fibers in the central nervous system. Myelin is necessary for the effective transmission of nerve impulses, and its deficiency leads to various neurological symptoms, such as slow motor development, ataxia, ataxic dysfunction, and other disorders. PMD most often affects males and is caused by mutations in the maser 1 (PLP1) gene, which encodes the main component of myelin. The disease is progressive and can significantly impair the quality of life of patients.<\/p>\n

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