{"id":12363,"date":"2024-10-11T22:52:55","date_gmt":"2024-10-11T20:52:55","guid":{"rendered":"https:\/\/valintermed.com\/?p=12363"},"modified":"2024-10-11T22:52:55","modified_gmt":"2024-10-11T20:52:55","slug":"osteoskleroz-autosomno-dominantnyy","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/autosomno-dominant-osteosclerosis\/","title":{"rendered":"Osteosclerosis Autosomal dominant"},"content":{"rendered":"
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Osteosclerosis, autosomal dominant, is a hereditary disease characterized by an abnormal increase in bone density. This is due to a disruption in the processes of bone formation and resorption, leading to its excessive deposition. The main pathogenetic mechanism of osteosclerosis is mutations in genes associated with bone remodeling, which disrupts the balance between osteoblasts and osteoclasts. The disease can manifest itself in various forms, but autosomal dominant osteosclerosis has its own unique clinical and molecular features that distinguish it from other bone pathologies.<\/p>\n

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