{"id":12360,"date":"2024-10-11T22:55:07","date_gmt":"2024-10-11T20:55:07","guid":{"rendered":"https:\/\/valintermed.com\/?p=12360"},"modified":"2024-10-11T22:55:07","modified_gmt":"2024-10-11T20:55:07","slug":"osteopoykiloz","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/osteopoietic-syndrome\/","title":{"rendered":"Osteopoikilosis"},"content":{"rendered":"
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Osteopoikilosis is a rare genetic disorder characterized by abnormal osteogenesis, leading to excessive bone formation and disruption of normal osteoclastic remodeling. This pathology often occurs against the background of mutations in the genes responsible for the development of osteoclasts, which leads to a disruption of their function and subsequent accumulation of mineral components in bone tissue. As a result, changes in the structure and density of bones are observed, which can lead to their pathological strength, as well as an increased risk of fractures and other complications. Osteopoikilosis can also be accompanied by clinical manifestations such as pain syndrome, limited mobility, and various systemic disorders.<\/p>\n

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