{"id":12285,"date":"2024-10-12T00:12:07","date_gmt":"2024-10-11T22:12:07","guid":{"rendered":"https:\/\/valintermed.com\/?p=12285"},"modified":"2024-10-12T00:12:07","modified_gmt":"2024-10-11T22:12:07","slug":"sindrom-nogtya-nadkolennika","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/knee-joint-syndrome\/","title":{"rendered":"Nail-patella syndrome"},"content":{"rendered":"
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Nail-patella syndrome (phalangeal-patellar junction syndrome) is a rare genetic disorder characterized by characteristic abnormalities in the development of nails, joints, and other body systems. The main clinical manifestation of this syndrome is changes in the structure of the nails, including hypoplasia, dysplasia, and underdevelopment, which may be accompanied by deformities of the patella and other joints. The disease is associated with disturbances in the formation and functioning of the mesodermal origin, which leads to complex pathology affecting the musculoskeletal system and dermatological structures. Diagnosis requires a comprehensive approach, including clinical, instrumental, and laboratory studies to confirm genetic abnormalities and exclude other diseases with similar symptoms. <\/p>\n

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