{"id":12277,"date":"2024-10-12T00:15:23","date_gmt":"2024-10-11T22:15:23","guid":{"rendered":"https:\/\/valintermed.com\/?p=12277"},"modified":"2024-10-12T00:15:23","modified_gmt":"2024-10-11T22:15:23","slug":"sindrom-negeli-franchesketti-yadassona","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/sindrom-negeli-franchesketti-yadassona\/","title":{"rendered":"Naegeli-Franceschetti-Jadassohn syndrome"},"content":{"rendered":"<div class=\"fpm_start\"><\/div>\n<p>Naegeli-Franceschetti-Jadassohn syndrome (NFJS) is a rare disease that belongs to a group of inherited disorders characterized by multiple malformations, including connective tissue abnormalities and systemic complications. The clinical picture of the disease can vary from mild manifestations to severe life-threatening conditions. The main symptoms include growth disorders, osteoporosis, skeletal deformities, as well as altered skin structure and anomalies of internal organs. It should be noted that NFJS affects not only the physical health, but also the psychoemotional state of patients, which is due to their noticeable physical disabilities and \/ or accompanying diseases.<\/p>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_83 counter-flat ez-toc-counter ez-toc-light-blue ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Content<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 eztoc-toggle-hide-by-default' ><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/sindrom-negeli-franchesketti-yadassona\/#%D0%98%D1%81%D1%82%D0%BE%D1%80%D0%B8%D1%8F_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F_%D0%B8_%D0%B8%D0%BD%D1%82%D0%B5%D1%80%D0%B5%D1%81%D0%BD%D1%8B%D0%B5_%D0%B8%D1%81%D1%82%D0%BE%D1%80%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B8%D0%B5_%D1%84%D0%B0%D0%BA%D1%82%D1%8B\" >History of the disease and interesting historical facts<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/sindrom-negeli-franchesketti-yadassona\/#%D0%AD%D0%BF%D0%B8%D0%B4%D0%B5%D0%BC%D0%B8%D0%BE%D0%BB%D0%BE%D0%B3%D0%B8%D1%8F\" >Epidemiology<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/sindrom-negeli-franchesketti-yadassona\/#%D0%93%D0%B5%D0%BD%D0%B5%D1%82%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B0%D1%8F_%D0%BF%D1%80%D0%B5%D0%B4%D1%80%D0%B0%D1%81%D0%BF%D0%BE%D0%BB%D0%BE%D0%B6%D0%B5%D0%BD%D0%BD%D0%BE%D1%81%D1%82%D1%8C_%D0%BA_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%BC%D1%83_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8E\" >Genetic predisposition to this disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/sindrom-negeli-franchesketti-yadassona\/#%D0%A4%D0%B0%D0%BA%D1%82%D0%BE%D1%80%D1%8B_%D1%80%D0%B8%D1%81%D0%BA%D0%B0_%D0%B2%D0%BE%D0%B7%D0%BD%D0%B8%D0%BA%D0%BD%D0%BE%D0%B2%D0%B5%D0%BD%D0%B8%D1%8F_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >Risk factors for the development of this disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/sindrom-negeli-franchesketti-yadassona\/#%D0%94%D0%B8%D0%B0%D0%B3%D0%BD%D0%BE%D1%81%D1%82%D0%B8%D0%BA%D0%B0_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >Diagnosis of this disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/sindrom-negeli-franchesketti-yadassona\/#%D0%9B%D0%B5%D1%87%D0%B5%D0%BD%D0%B8%D0%B5\" >Treatment<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/sindrom-negeli-franchesketti-yadassona\/#%D0%A1%D0%BF%D0%B8%D1%81%D0%BE%D0%BA_%D0%BB%D0%B5%D0%BA%D0%B0%D1%80%D1%81%D1%82%D0%B2_%D0%BF%D1%80%D0%B8%D0%BC%D0%B5%D0%BD%D1%8F%D0%B5%D0%BC%D1%8B%D1%85_%D0%B4%D0%BB%D1%8F_%D0%BB%D0%B5%D1%87%D0%B5%D0%BD%D0%B8%D1%8F_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >List of medications used to treat this disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/sindrom-negeli-franchesketti-yadassona\/#%D0%9C%D0%BE%D0%BD%D0%B8%D1%82%D0%BE%D1%80%D0%B8%D0%BD%D0%B3_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >Disease monitoring<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/sindrom-negeli-franchesketti-yadassona\/#%D0%92%D0%BE%D0%B7%D1%80%D0%B0%D1%81%D1%82%D0%BD%D1%8B%D0%B5_%D0%BE%D1%81%D0%BE%D0%B1%D0%B5%D0%BD%D0%BD%D0%BE%D1%81%D1%82%D0%B8_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >Age-related features of the disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/sindrom-negeli-franchesketti-yadassona\/#%D0%92%D0%BE%D0%BF%D1%80%D0%BE%D1%81%D1%8B_%D0%B8_%D0%BE%D1%82%D0%B2%D0%B5%D1%82%D1%8B\" >Questions and Answers<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"%D0%98%D1%81%D1%82%D0%BE%D1%80%D0%B8%D1%8F_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F_%D0%B8_%D0%B8%D0%BD%D1%82%D0%B5%D1%80%D0%B5%D1%81%D0%BD%D1%8B%D0%B5_%D0%B8%D1%81%D1%82%D0%BE%D1%80%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B8%D0%B5_%D1%84%D0%B0%D0%BA%D1%82%D1%8B\"><\/span>History of the disease and interesting historical facts<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>N\u00e4geli-Franceschetti-Jadassohn syndrome was first described in the medical literature at the beginning of the 20th century, when several researchers, including N\u00e4geli, Franceschetti, and Jadassohn, independently described various manifestations of this disease. Interesting facts about N\u00e4geli-Franceschetti-Jadassohn syndrome are the diversity of its clinical manifestations: although the disease has a genetic basis, its severity and typicality of symptoms can vary significantly even among members of the same family. In the following decades, many studies were conducted on the genetic mechanisms underlying the development of the syndrome, but many aspects of its pathogenesis remain unexplored. Based on this fact, some researchers suggest the presence of as yet unidentified mutations.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%AD%D0%BF%D0%B8%D0%B4%D0%B5%D0%BC%D0%B8%D0%BE%D0%BB%D0%BE%D0%B3%D0%B8%D1%8F\"><\/span>Epidemiology<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>According to statistics, the incidence of N\u00e4geli-Franceschetti-Jadassohn syndrome is approximately 1 case per 500,000-1,000,000 live births, which places the disease in the rare category. However, the exact figure may vary depending on the region, which is due to historical, ethnic and environmental characteristics. Due to the rarity of the disease, many doctors may not recognize it in the early stages, which complicates further assessment of the true prevalence of N\u00e4geli-Franceschetti-Jadassohn syndrome in different populations. In some countries, there are specialized registries that monitor patients with rare diseases, which allows for a more accurate assessment of statistics and the development of effective treatment methods.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%93%D0%B5%D0%BD%D0%B5%D1%82%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B0%D1%8F_%D0%BF%D1%80%D0%B5%D0%B4%D1%80%D0%B0%D1%81%D0%BF%D0%BE%D0%BB%D0%BE%D0%B6%D0%B5%D0%BD%D0%BD%D0%BE%D1%81%D1%82%D1%8C_%D0%BA_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%BC%D1%83_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8E\"><\/span>Genetic predisposition to this disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>N\u00e4geli-Franceschetti-Jadassohn syndrome is associated with mutations in a number of genes, the most significant of which are the COL2A1 and COL11A1 genes responsible for collagen synthesis. These proteins play a key role in maintaining the structure and elasticity of connective tissue, making them vital for the normal functioning of the musculoskeletal system. In some cases, autosomal dominant mutations are observed, which are passed from parent to offspring with a probability of 50%. Genetic testing and predisposition to the disease can be an important tool for early diagnosis and intervention, improving the quality of life of patients.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%A4%D0%B0%D0%BA%D1%82%D0%BE%D1%80%D1%8B_%D1%80%D0%B8%D1%81%D0%BA%D0%B0_%D0%B2%D0%BE%D0%B7%D0%BD%D0%B8%D0%BA%D0%BD%D0%BE%D0%B2%D0%B5%D0%BD%D0%B8%D1%8F_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>Risk factors for the development of this disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Given the hereditary nature of Naegeli-Franceschetti-Jadassohn Syndrome, the main risk factor is the presence of similar diseases in close relatives. However, in addition to genetic factors, there are also physical and chemical factors that can aggravate the course of the disease or contribute to its manifestation. Such factors include: <\/p>\n<ul>\n<li>Environmental living conditions (e.g. environmental pollution).<\/li>\n<li>Exposure to toxic chemicals (eg heavy metals).<\/li>\n<li>Methods of pregnancy management (for example, use of certain medications or alcohol).<\/li>\n<li>Presence of diseases or infections in the mother during pregnancy.<\/li>\n<\/ul>\n<p>These factors may not cause the disease directly, but they significantly affect its manifestation and course.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%94%D0%B8%D0%B0%D0%B3%D0%BD%D0%BE%D1%81%D1%82%D0%B8%D0%BA%D0%B0_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>Diagnosis of this disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Diagnosis of Naegeli-Franceschetti-Jadassohn syndrome is based on a comprehensive approach, including an assessment of clinical symptoms, family history, and laboratory test results. The main symptoms of the disease may include:<\/p>\n<ul>\n<li>Skeletal deformities (eg scoliosis, dysplasia).<\/li>\n<li>Growth and developmental disorders.<\/li>\n<li>Problems with connective tissue, including skin and joints.<\/li>\n<li>Other systemic disorders.<\/li>\n<\/ul>\n<p>Laboratory testing may include genetic testing for mutations, and radiological examinations (eg, x-rays, MRI) are used to detect skeletal abnormalities. Other forms of diagnostic testing may include ultrasound and soft tissue biopsy. Differential diagnosis is important to rule out other conditions that may have similar presentations, such as other genetic syndromes or metabolic disorders.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%9B%D0%B5%D1%87%D0%B5%D0%BD%D0%B8%D0%B5\"><\/span>Treatment<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Treatment of Naegeli-Franceschetti-Jadassohn syndrome requires a multidisciplinary approach, including orthopedists, geneticists, dermatologists and other specialists. General treatment is aimed at symptomatic relief and improving the quality of life of patients. Pharmacological treatment may include:<\/p><script data-noptimize=\"\" data-wpfc-render=\"false\">\nfpm_start( \"true\" );\n<\/script>\n\n<ul>\n<li>Taking vitamins (for example, vitamin D to strengthen bones).<\/li>\n<li>Anti-inflammatory drugs for pain relief.<\/li>\n<li>Products that improve microcirculation.<\/li>\n<\/ul>\n<p>Surgery may be necessary to correct deformities or restore function to damaged joints. Other treatments may include physical therapy and rehabilitation to improve mobility and function.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%A1%D0%BF%D0%B8%D1%81%D0%BE%D0%BA_%D0%BB%D0%B5%D0%BA%D0%B0%D1%80%D1%81%D1%82%D0%B2_%D0%BF%D1%80%D0%B8%D0%BC%D0%B5%D0%BD%D1%8F%D0%B5%D0%BC%D1%8B%D1%85_%D0%B4%D0%BB%D1%8F_%D0%BB%D0%B5%D1%87%D0%B5%D0%BD%D0%B8%D1%8F_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>List of medications used to treat this disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The main groups of drugs used to relieve the symptoms and complications of Naegeli-Franceschetti-Jadassohn syndrome include:<\/p>\n<ul>\n<li>Bisphosphonates to improve bone mineralization.<\/li>\n<li>Nonsteroidal anti-inflammatory drugs (NSAIDs) to relieve inflammation.<\/li>\n<li>Painkillers to control pain.<\/li>\n<li>Contraceptive drugs to prevent additional hormonal disorders.<\/li>\n<\/ul>\n<p>It is important to note that medications should only be prescribed by a specialist, taking into account the individual characteristics of the patient.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%9C%D0%BE%D0%BD%D0%B8%D1%82%D0%BE%D1%80%D0%B8%D0%BD%D0%B3_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>Disease monitoring<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Monitoring of Naegeli-Franceschetti-Jadassohn syndrome involves regular examinations aimed at assessing the patient&#039;s condition, functions, and possible complications. Control stages include:<\/p>\n<ul>\n<li>Regular visits to medical specialists.<\/li>\n<li>Periodic genetic testing.<\/li>\n<li>Radiation studies to assess bone health.<\/li>\n<\/ul>\n<p>The prognosis for patients with the syndrome can vary depending on the severity of symptoms and the presence of comorbidities. Complications can include infections, musculoskeletal disorders, and cancer.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%92%D0%BE%D0%B7%D1%80%D0%B0%D1%81%D1%82%D0%BD%D1%8B%D0%B5_%D0%BE%D1%81%D0%BE%D0%B1%D0%B5%D0%BD%D0%BD%D0%BE%D1%81%D1%82%D0%B8_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>Age-related features of the disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Naegeli-Franceschetti-Jadassohn syndrome may present differently depending on the age group of the patient. In newborns, specific symptoms may include severe developmental abnormalities, while in children and adolescents, their manifestations may be smoothed out, but with increasing physical activity, complaints of joint pain and other systemic disorders appear. In adults, the condition may significantly worsen as the disease progresses, which can lead to loss of functionality and a decrease in quality of life.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%92%D0%BE%D0%BF%D1%80%D0%BE%D1%81%D1%8B_%D0%B8_%D0%BE%D1%82%D0%B2%D0%B5%D1%82%D1%8B\"><\/span>Questions and Answers<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<ul>\n<li><strong>What are the main symptoms of Naegeli-Franceschetti-Jadassohn syndrome?<\/strong> The main symptoms include connective tissue abnormalities, skeletal deformities, growth and developmental disorders, and other systemic disorders.<\/li>\n<li><strong>How is this disease diagnosed?<\/strong> Diagnosis includes evaluation of clinical manifestations, genetic testing, and radiological examinations to exclude similar diseases.<\/li>\n<li><strong>What is the prognosis for patients with Naegeli-Franceschetti-Jadassohn syndrome?<\/strong> The prognosis varies depending on the severity of symptoms and the presence of complications, but with proper diagnosis and treatment, patients can significantly improve their quality of life.<\/li>\n<li><strong>What factors can aggravate the disease?<\/strong> Risk factors include genetic predisposition, pregnancy management, and environmental and chemical exposures.<\/li>\n<li><strong>What treatment is used to improve the condition of patients?<\/strong> Treatment may include pharmacological agents, physical therapy, and surgical methods to correct abnormalities and improve quality of life.<\/li>\n<\/ul>\n<div class=\"fpm_end\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Naegeli-Franceschetti-Jadassohn syndrome (NFJS) is a rare disorder that belongs to a group of inherited disorders characterized by multiple developmental defects, including abnormalities<\/p>","protected":false},"author":1,"featured_media":21307,"comment_status":"open","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[298],"tags":[],"class_list":["post-12277","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medlibrary"],"_links":{"self":[{"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/posts\/12277","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/comments?post=12277"}],"version-history":[{"count":1,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/posts\/12277\/revisions"}],"predecessor-version":[{"id":14802,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/posts\/12277\/revisions\/14802"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/media\/21307"}],"wp:attachment":[{"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/media?parent=12277"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/categories?post=12277"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/tags?post=12277"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}