{"id":12235,"date":"2025-01-14T17:25:45","date_gmt":"2025-01-14T16:25:45","guid":{"rendered":"https:\/\/valintermed.com\/?p=12235"},"modified":"2025-01-14T17:25:45","modified_gmt":"2025-01-14T16:25:45","slug":"neyrofibromatoz-1-tipa-nf1","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/neurofibromatosis-type-1-nf1\/","title":{"rendered":"Neurofibromatosis type 1 (NF1)"},"content":{"rendered":"
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Neurofibromatosis type 1 (NF1) is an inherited disorder characterized by multiple neurofibromas, bone dysplasia, skin changes, and additional neurological manifestations. The disorder has an autosomal dominant inheritance pattern, meaning that the affected gene can be passed from one parent to the child with a probability of 50%. The most characteristic features include caf\u00e9-au-lait spots, neurofibromas (tumors that develop from the sheaths of peripheral nerves), and skeletal changes. Clinical manifestations can range from mild and inconsequential to severe, affecting quality of life. The disease not only affects physical health, but can also have a significant impact on the psychosocial well-being of patients.<\/p>\n

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