{"id":12119,"date":"2025-03-13T21:22:52","date_gmt":"2025-03-13T20:22:52","guid":{"rendered":"https:\/\/valintermed.com\/?p=12119"},"modified":"2025-03-13T21:22:52","modified_gmt":"2025-03-13T20:22:52","slug":"mukopolisaharidoz-tipa-3b-mps-iiib-sindrom-sanfilippo-b","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/mukopolisaharidoz-tipa-3b-mps-iiib-sindrom-sanfilippo-b\/","title":{"rendered":"Mucopolysaccharidosis type 3B (MPS IIIB, Sanfilippo syndrome B)"},"content":{"rendered":"
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Mucopolysaccharidosis type 3B (MPS IIIB, Sanfilippo syndrome B) is an inherited metabolic disorder belonging to the group of mucopolysaccharidoses. This rare disorder is caused by a deficiency of the enzyme N-acetyl-alpha-glucosaminidase, which leads to the accumulation of heparan sulfate in various tissues of the body. Clinical and laboratory manifestations of MPS IIIB usually begin to appear in early childhood and may include mental and physical developmental delays, behavioral disorders, and progressive neurological symptoms. The nature of the disease makes it progressive, which requires a comprehensive approach to diagnosis, treatment, and monitoring of patients.<\/p>\n

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