{"id":11919,"date":"2025-06-17T06:00:50","date_gmt":"2025-06-17T04:00:50","guid":{"rendered":"https:\/\/valintermed.com\/?p=11919"},"modified":"2025-06-17T06:00:50","modified_gmt":"2025-06-17T04:00:50","slug":"sindrom-leya","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/leya-syndrome\/","title":{"rendered":"Leigh syndrome"},"content":{"rendered":"
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Leigh syndrome is a rare mitochondrial disorder characterized by acute necrosis of the basal ganglia and brainstem structures. This pathology manifests itself in severe neurological disorders, including regression of psychomotor development, seizures, muscle hypotonia and respiratory disorders. The disease has a progressive course and often leads to death in early childhood. The pathophysiological basis of the disease is a violation of oxidative phosphorylation in the mitochondria, which leads to energy deficiency of neurons.<\/p>\n

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