{"id":11877,"date":"2025-07-25T20:57:26","date_gmt":"2025-07-25T18:57:26","guid":{"rendered":"https:\/\/valintermed.com\/?p=11877"},"modified":"2025-07-25T20:57:26","modified_gmt":"2025-07-25T18:57:26","slug":"lissentsefaliya-1","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/lissentsefaliya-1\/","title":{"rendered":"Lissencephaly 1"},"content":{"rendered":"
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Lissencephaly is a neuropsychiatric disorder characterized by abnormal development of the cerebral cortex, in which the normal convolutions (gyri) are absent and the surface is smooth. This leads to a disruption of the brain's functional capabilities and can manifest itself in various neurological and mental disorders. Lissencephaly occurs as a result of abnormalities in the embryonic period, which leads to abnormalities in the migration of neurons, which in turn affects the formation of the cerebral cortex. The disease can manifest itself in a wide range of symptoms, from severe mental retardation to movement disorders and epilepsy, depending on the severity of the changes.<\/p>\n

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