{"id":11876,"date":"2025-07-25T20:58:06","date_gmt":"2025-07-25T18:58:06","guid":{"rendered":"https:\/\/valintermed.com\/?p=11876"},"modified":"2025-07-25T20:58:06","modified_gmt":"2025-07-25T18:58:06","slug":"lissentsefaliya","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/lissentefaliya\/","title":{"rendered":"Lissencephaly"},"content":{"rendered":"
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Lissencephaly is a rare neurogenetic disorder characterized by abnormal development of the cerebral cortex, resulting in the absence or underdevelopment of characteristic sulci and gyri. The diagnosis is often made during early childhood, when parents begin to notice abnormal motor development, as well as neurological disorders such as epilepsy and psychomotor delay. Lissencephaly can be caused by a variety of factors, including genetic mutations and thermal effects on fetal development in the womb. Because the disorder has variable severity, clinical manifestations can range from mild mental retardation to severe neurological impairment.<\/p>\n

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