{"id":11835,"date":"2025-07-25T23:00:08","date_gmt":"2025-07-25T21:00:08","guid":{"rendered":"https:\/\/valintermed.com\/?p=11835"},"modified":"2025-07-25T23:00:08","modified_gmt":"2025-07-25T21:00:08","slug":"konechnostno-poyasnaya-myshechnaya-distrofiya","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/limb-belt-myocardial-dystrophy\/","title":{"rendered":"Limb-girdle muscular dystrophy"},"content":{"rendered":"
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Limb-girdle muscular dystrophy (LGMD) is a genetic disorder characterized by progressive weakening and atrophy of skeletal muscles. The disorder primarily affects proximal muscle groups, including the shoulder girdle, pelvic girdle, and limbs. Symptoms often appear in childhood or adolescence, but in some cases the onset may occur at a later period. The disorder is caused by mutations in genes that control the structure and function of muscle fibers, leading to dystrophy and replacement of muscle tissue with fibrous and fatty tissue. The course of the disease varies from person to person, with variability in the timing and severity of symptoms, requiring a careful approach to diagnosis and treatment.<\/p>\n

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