{"id":11786,"date":"2025-07-26T01:28:32","date_gmt":"2025-07-25T23:28:32","guid":{"rendered":"https:\/\/valintermed.com\/?p=11786"},"modified":"2025-07-26T01:28:32","modified_gmt":"2025-07-25T23:28:32","slug":"sindrom-kulena-de-friza","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/cold-sore-syndrome\/","title":{"rendered":"Coolen de Vries syndrome"},"content":{"rendered":"
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Koolen de Vries syndrome (KdV) is a hereditary disease that belongs to a group of disorders that affect multiple body systems. It is characterized by a combination of various features, such as dysplastic skin changes, bone abnormalities, and a predisposition to cancer, especially sarcomas and carcinomas. The most striking clinical manifestations of the syndrome are angular facial features, hypopigmentation of the skin and hair, and impaired growth and development. The disease manifests itself in childhood and requires a comprehensive approach to diagnosis and treatment. In accordance with modern requirements for medical practice, knowledge of Koolen de Vries syndrome is important for timely detection and initiation of therapeutic measures.<\/p>\n

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