{"id":11692,"date":"2025-07-26T06:25:42","date_gmt":"2025-07-26T04:25:42","guid":{"rendered":"https:\/\/valintermed.com\/?p=11692"},"modified":"2025-07-26T06:25:42","modified_gmt":"2025-07-26T04:25:42","slug":"zabolevanie-svyazannoe-s-igg4","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/disease-associated-with-igg4\/","title":{"rendered":"IgG4 related disease"},"content":{"rendered":"
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IgG4-related disease is a group of pathologies characterized by chronic inflammation, fibrosis, and the presence of IgG4-positive plasma cells in various organs. This disease, known as IgG4-associated disease, covers a wide range of clinical manifestations, including pancreatitis, unappreciated fibrotic processes in the lungs, kidneys, salivary and lacrimal glands, and systemic disorders. The underlying mechanism of this pathology is autoimmune reactions that are formed due to the inactivation of IgG4, which leads to the formation of a predominance of IgG4 antibodies and an active fibrotic process.<\/p>\n

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