{"id":11599,"date":"2025-07-26T10:58:01","date_gmt":"2025-07-26T08:58:01","guid":{"rendered":"https:\/\/valintermed.com\/?p=11599"},"modified":"2025-07-26T10:58:01","modified_gmt":"2025-07-26T08:58:01","slug":"nasledstvennaya-retinoblastoma","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/hereditary-retinoblastoma\/","title":{"rendered":"Hereditary retinoblastoma"},"content":{"rendered":"
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Hereditary retinoblastoma (HR) is a malignant tumor originating from the cells of the retina of the eye, which predominantly affects children, especially those under five years of age. The disease can manifest as a unilateral or bilateral lesion. The main mechanism of retinoblastoma development is a mutation in the genes responsible for the control of cell division and apoptosis, which leads to uncontrolled proliferation of cells in the retina. Although most cases of HR have a spontaneous mutation, the hereditary type of the disease is associated with the inheritance of abnormal alleles from parents. A family history of HR increases the risk of the disease in future generations, which emphasizes the importance of genetic counseling for potential relatives.<\/p>\n

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