{"id":11453,"date":"2025-07-26T18:25:14","date_gmt":"2025-07-26T16:25:14","guid":{"rendered":"https:\/\/valintermed.com\/?p=11453"},"modified":"2025-07-26T18:25:14","modified_gmt":"2025-07-26T16:25:14","slug":"vysokiy-uroven-holesterina","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/high-level-of-holesterina\/","title":{"rendered":"High cholesterol"},"content":{"rendered":"<div class=\"fpm_start\"><\/div>\n<p>High cholesterol is a serious medical problem associated with an increased risk of cardiovascular disease, strokes and other pathologies. Cholesterol, which is necessary for the formation of cell membranes and the synthesis of hormones, is normally present in the blood in certain concentrations. However, its excess, especially low-density lipoproteins (LDL), can lead to atherosclerosis and the formation of plaques in blood vessels, which in turn worsens the blood supply to organs and tissues, causing many dangerous conditions.<\/p>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_85 counter-flat ez-toc-counter ez-toc-light-blue ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Content<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 eztoc-toggle-hide-by-default' ><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/high-level-of-holesterina\/#%D0%98%D1%81%D1%82%D0%BE%D1%80%D0%B8%D1%8F_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F_%D0%B8_%D0%B8%D0%BD%D1%82%D0%B5%D1%80%D0%B5%D1%81%D0%BD%D1%8B%D0%B5_%D0%B8%D1%81%D1%82%D0%BE%D1%80%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B8%D0%B5_%D1%84%D0%B0%D0%BA%D1%82%D1%8B\" >History of the disease and interesting historical facts<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/high-level-of-holesterina\/#%D0%AD%D0%BF%D0%B8%D0%B4%D0%B5%D0%BC%D0%B8%D0%BE%D0%BB%D0%BE%D0%B3%D0%B8%D1%8F\" >Epidemiology<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/high-level-of-holesterina\/#%D0%93%D0%B5%D0%BD%D0%B5%D1%82%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B0%D1%8F_%D0%BF%D1%80%D0%B5%D0%B4%D1%80%D0%B0%D1%81%D0%BF%D0%BE%D0%BB%D0%BE%D0%B6%D0%B5%D0%BD%D0%BD%D0%BE%D1%81%D1%82%D1%8C\" >Genetic predisposition<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/high-level-of-holesterina\/#%D0%A4%D0%B0%D0%BA%D1%82%D0%BE%D1%80%D1%8B_%D1%80%D0%B8%D1%81%D0%BA%D0%B0_%D0%B2%D0%BE%D0%B7%D0%BD%D0%B8%D0%BA%D0%BD%D0%BE%D0%B2%D0%B5%D0%BD%D0%B8%D1%8F\" >Risk factors for occurrence<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/high-level-of-holesterina\/#%D0%94%D0%B8%D0%B0%D0%B3%D0%BD%D0%BE%D1%81%D1%82%D0%B8%D0%BA%D0%B0_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >Diagnosis of this disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/high-level-of-holesterina\/#%D0%9B%D0%B5%D1%87%D0%B5%D0%BD%D0%B8%D0%B5\" >Treatment<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/high-level-of-holesterina\/#%D0%A1%D0%BF%D0%B8%D1%81%D0%BE%D0%BA_%D0%BB%D0%B5%D0%BA%D0%B0%D1%80%D1%81%D1%82%D0%B2_%D0%BF%D1%80%D0%B8%D0%BC%D0%B5%D0%BD%D1%8F%D0%B5%D0%BC%D1%8B%D1%85_%D0%B4%D0%BB%D1%8F_%D0%BB%D0%B5%D1%87%D0%B5%D0%BD%D0%B8%D1%8F_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >List of medications used to treat this disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/high-level-of-holesterina\/#%D0%9C%D0%BE%D0%BD%D0%B8%D1%82%D0%BE%D1%80%D0%B8%D0%BD%D0%B3_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >Disease monitoring<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/high-level-of-holesterina\/#%D0%92%D0%BE%D0%B7%D1%80%D0%B0%D1%81%D1%82%D0%BD%D1%8B%D0%B5_%D0%BE%D1%81%D0%BE%D0%B1%D0%B5%D0%BD%D0%BD%D0%BE%D1%81%D1%82%D0%B8_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >Age-related features of the disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/high-level-of-holesterina\/#%D0%92%D0%BE%D0%BF%D1%80%D0%BE%D1%81%D1%8B_%D0%B8_%D0%BE%D1%82%D0%B2%D0%B5%D1%82%D1%8B\" >Questions and Answers<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/high-level-of-holesterina\/#%D0%A1%D0%BE%D0%B2%D0%B5%D1%82%D1%8B_%D0%BE%D1%82_%D0%B4%D0%BE%D0%BA%D1%82%D0%BE%D1%80%D0%B0_%D0%9E%D0%BB%D0%B5%D0%B3%D0%B0_%D0%9A%D0%BE%D1%80%D0%B6%D0%B8%D0%BA%D0%BE%D0%B2%D0%B0\" >Advice from Dr. Oleg Korzhikov<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"%D0%98%D1%81%D1%82%D0%BE%D1%80%D0%B8%D1%8F_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F_%D0%B8_%D0%B8%D0%BD%D1%82%D0%B5%D1%80%D0%B5%D1%81%D0%BD%D1%8B%D0%B5_%D0%B8%D1%81%D1%82%D0%BE%D1%80%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B8%D0%B5_%D1%84%D0%B0%D0%BA%D1%82%D1%8B\"><\/span>History of the disease and interesting historical facts<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The problem of elevated cholesterol levels and their impact on human health has been known since ancient times. In the 19th century, cholesterol was first isolated from bile, and in the 1930s, its connection with atherosclerosis was proven. In the 1950s, studies began actively recording changes in the cardiovascular sphere associated with cholesterol levels. In the 1980s, the first evidence-based recommendations for cholesterol control appeared, and since then this area has become one of the key components of cardiology and chronic disease therapy.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%AD%D0%BF%D0%B8%D0%B4%D0%B5%D0%BC%D0%B8%D0%BE%D0%BB%D0%BE%D0%B3%D0%B8%D1%8F\"><\/span>Epidemiology<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>According to the World Health Organization (WHO), high cholesterol levels are found in almost 40% of the adult population of the planet. Epidemiological studies show that this indicator varies significantly depending on the geographical location, level of economic development of countries and dietary habits of the population. For example, in countries with a high standard of living, such as the United States and Canada, the prevalence of dyslipidemia reaches 50%. Such data are confirmed by numerous epidemiological studies that record a stable trend towards an increase in pathologies associated with high cholesterol.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%93%D0%B5%D0%BD%D0%B5%D1%82%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B0%D1%8F_%D0%BF%D1%80%D0%B5%D0%B4%D1%80%D0%B0%D1%81%D0%BF%D0%BE%D0%BB%D0%BE%D0%B6%D0%B5%D0%BD%D0%BD%D0%BE%D1%81%D1%82%D1%8C\"><\/span>Genetic predisposition<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Genetic predisposition to high cholesterol can manifest itself in inherited conditions such as hypercholesterolemia. The main mutations affect genes involved in lipid metabolism, including the LDLR gene, which codes for the receptor for LDL, and the APOB gene, which encodes apolipoprotein B, the backbone of LDL. Mutations in these genes can reduce the ability of cells to take up cholesterol from the blood, leading to its accumulation. Given the complexity of gene-environment interactions, hereditary factors must be considered when assessing risk.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%A4%D0%B0%D0%BA%D1%82%D0%BE%D1%80%D1%8B_%D1%80%D0%B8%D1%81%D0%BA%D0%B0_%D0%B2%D0%BE%D0%B7%D0%BD%D0%B8%D0%BA%D0%BD%D0%BE%D0%B2%D0%B5%D0%BD%D0%B8%D1%8F\"><\/span>Risk factors for occurrence<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>There are many factors that contribute to increased cholesterol levels in the body. The main ones are:<\/p>\n<ul>\n<li>Poor diet (high in saturated and trans fats)<\/li>\n<li>Sedentary lifestyle and physical inactivity<\/li>\n<li>Obesity and overweight<\/li>\n<li>Smoking and drinking alcohol<\/li>\n<li>Age and gender (men are more at risk at a younger age)<\/li>\n<li>Concomitant diseases (diabetes, hypertension)<\/li>\n<\/ul>\n<p>These factors may interact with each other to increase the overall risk of developing dyslipidemia and related diseases.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%94%D0%B8%D0%B0%D0%B3%D0%BD%D0%BE%D1%81%D1%82%D0%B8%D0%BA%D0%B0_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>Diagnosis of this disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Diagnosis of high cholesterol involves several steps:<\/p>\n<ul>\n<li>Main symptoms: in most cases the disease is asymptomatic, however manifestations of atherosclerosis (chest pain, shortness of breath) are possible.<\/li>\n<li>Laboratory tests: Blood test for lipid spectrum, which includes determination of the level of total cholesterol, LDL, HDL and triglycerides.<\/li>\n<li>Radiological examinations: ultrasound diagnostics of blood vessels, allowing to assess the presence of atherosclerotic plaques.<\/li>\n<li>Other diagnostic tests include electrocardiography, which can reveal signs of coronary heart disease.<\/li>\n<li>Differential diagnosis: ruling out other causes of elevated cholesterol levels, such as hypothyroidism or liver disease.<\/li>\n<\/ul>\n<p>These methods allow us to determine the degree of risk and select the correct therapeutic approaches.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%9B%D0%B5%D1%87%D0%B5%D0%BD%D0%B8%D0%B5\"><\/span>Treatment<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Treatment for high cholesterol involves several approaches:<\/p><script data-noptimize=\"\" data-wpfc-render=\"false\">\nfpm_start( \"true\" );\n<\/script>\n\n<ul>\n<li>General treatment: lifestyle changes, giving up bad habits, switching to a healthy diet.<\/li>\n<li>Pharmacological treatment: administration of statins and other lipid-lowering drugs.<\/li>\n<li>Surgical treatment: Coronary artery bypass grafting or angioplasty may be required for severe cases of atherosclerosis.<\/li>\n<li>Other treatments include phytosterols and lipid profile-improving supplements.<\/li>\n<\/ul>\n<p>Each of these points requires an individual approach and consultation with medical professionals.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%A1%D0%BF%D0%B8%D1%81%D0%BE%D0%BA_%D0%BB%D0%B5%D0%BA%D0%B0%D1%80%D1%81%D1%82%D0%B2_%D0%BF%D1%80%D0%B8%D0%BC%D0%B5%D0%BD%D1%8F%D0%B5%D0%BC%D1%8B%D1%85_%D0%B4%D0%BB%D1%8F_%D0%BB%D0%B5%D1%87%D0%B5%D0%BD%D0%B8%D1%8F_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>List of medications used to treat this disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The main classes of drugs used to lower cholesterol include:<\/p>\n<ul>\n<li>Statins (atorvastatin, simvastatin, rosuvastatin)<\/li>\n<li>Fibrates (fenofibrate, gemfibrozil)<\/li>\n<li>A nicotinic acid<\/li>\n<li>Bile acid secretors (colestipol, cholestyramine)<\/li>\n<li>PCSK9 inhibitors (alirocumab, evolocumab)<\/li>\n<\/ul>\n<p>Each of these drugs has its own indications and contraindications, which necessitates an individual approach.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%9C%D0%BE%D0%BD%D0%B8%D1%82%D0%BE%D1%80%D0%B8%D0%BD%D0%B3_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>Disease monitoring<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Monitoring cholesterol levels is necessary during treatment:<\/p>\n<ul>\n<li>Control stages: regular lipid profile checks every 3-6 months<\/li>\n<li>Prognosis: with timely lifestyle correction and therapy, the prognosis is favorable<\/li>\n<li>Complications: Acute conditions such as myocardial infarction or stroke may occur if left untreated.<\/li>\n<\/ul>\n<p>Such measures allow timely detection of deterioration of the condition and adjustment of therapy.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%92%D0%BE%D0%B7%D1%80%D0%B0%D1%81%D1%82%D0%BD%D1%8B%D0%B5_%D0%BE%D1%81%D0%BE%D0%B1%D0%B5%D0%BD%D0%BD%D0%BE%D1%81%D1%82%D0%B8_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>Age-related features of the disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The course of the pathology in different age groups can differ significantly:<\/p>\n<ul>\n<li>Children and young people: often asymptomatic, detected only during medical examination.<\/li>\n<li>Middle age: Pronounced symptoms begin to appear against the background of stress and poor nutrition.<\/li>\n<li>Elderly people: high predisposition to cardiovascular diseases, careful diagnosis and monitoring is necessary.<\/li>\n<\/ul>\n<p>This information is important for developing preventive and treatment programs.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%92%D0%BE%D0%BF%D1%80%D0%BE%D1%81%D1%8B_%D0%B8_%D0%BE%D1%82%D0%B2%D0%B5%D1%82%D1%8B\"><\/span>Questions and Answers<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<ul>\n<li><strong>How often should you check your cholesterol levels?<\/strong> It is recommended that the test be performed every 4-6 years for healthy people over 20 years of age, and more often for people with risk factors.<\/li>\n<li><strong>What foods are good for lowering cholesterol?<\/strong> Oatmeal, fish, olive oil, nuts, fruits and vegetables are useful.<\/li>\n<li><strong>What treatment is considered the most effective?<\/strong> A combination approach that combines lifestyle changes and drug therapy is considered the most effective.<\/li>\n<li><strong>Can stress affect cholesterol levels?<\/strong> Yes, chronic stress can contribute to high blood cholesterol levels.<\/li>\n<li><strong>What are the first signs of high cholesterol?<\/strong> Initially, the disease is usually asymptomatic; symptoms of atherosclerosis may appear later.<\/li>\n<\/ul>\n<h2><span class=\"ez-toc-section\" id=\"%D0%A1%D0%BE%D0%B2%D0%B5%D1%82%D1%8B_%D0%BE%D1%82_%D0%B4%D0%BE%D0%BA%D1%82%D0%BE%D1%80%D0%B0_%D0%9E%D0%BB%D0%B5%D0%B3%D0%B0_%D0%9A%D0%BE%D1%80%D0%B6%D0%B8%D0%BA%D0%BE%D0%B2%D0%B0\"><\/span>Advice from Dr. Oleg Korzhikov<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Dr. Oleg Korzhikov advises: \u201cMonitor your cholesterol level from a young age. Regular checks will help identify the problem at an early stage. You can start the process of changing your diet with small steps, replacing saturated fats with healthy unsaturated fats. Don\u2019t forget about physical activity: walking and playing sports can significantly improve your condition. If you are at risk, be sure to discuss possible preventive measures with your doctor. Remember that monitoring your cholesterol level is an investment in your health!\u201d<\/p>\n<div class=\"fpm_end\"><\/div>","protected":false},"excerpt":{"rendered":"<p>High cholesterol is a serious medical problem associated with an increased risk of developing cardiovascular disease, stroke, and other pathologies. Cholesterol,<\/p>","protected":false},"author":1,"featured_media":18931,"comment_status":"open","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[298],"tags":[],"class_list":["post-11453","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medlibrary"],"_links":{"self":[{"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/posts\/11453","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/comments?post=11453"}],"version-history":[{"count":1,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/posts\/11453\/revisions"}],"predecessor-version":[{"id":15762,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/posts\/11453\/revisions\/15762"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/media\/18931"}],"wp:attachment":[{"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/media?parent=11453"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/categories?post=11453"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/tags?post=11453"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}