{"id":11412,"date":"2025-07-26T20:27:36","date_gmt":"2025-07-26T18:27:36","guid":{"rendered":"https:\/\/valintermed.com\/?p=11412"},"modified":"2025-07-26T20:27:36","modified_gmt":"2025-07-26T18:27:36","slug":"sindrom-gardnera","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/gardner-s-syndrome\/","title":{"rendered":"Gardner's syndrome"},"content":{"rendered":"
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Gardner syndrome (GS) is a genetic disorder belonging to the group of hereditary polyposis syndromes. It is characterized by multiple adenomatous polyps of the colon, which have a high risk of malignancy. Along with polyposis, various extraintestinal manifestations are observed, such as osteomas, soft tissue tumors and even, in some cases, dermoid cysts. The syndrome is part of familial polyposis (FAP) and is caused by mutations in the APC (adenomatous polyposis coli) gene, which plays a key role in the regulation of the cell cycle and the process of apoptosis. Thus, the disease is a complex interaction between genetic disorders and pronounced phenotypic manifestations.<\/p>\n

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