{"id":11365,"date":"2025-07-26T22:54:06","date_gmt":"2025-07-26T20:54:06","guid":{"rendered":"https:\/\/valintermed.com\/?p=11365"},"modified":"2025-07-26T22:54:06","modified_gmt":"2025-07-26T20:54:06","slug":"glitsinovaya-entsefalopatiya","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/glitsinovaya-entsefalopatiya\/","title":{"rendered":"Glycine encephalopathy"},"content":{"rendered":"
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Glycine encephalopathy (GE) is a rare hereditary disease that belongs to a group of metabolic disorders initiated by an abnormality in amino acid metabolism. The main pathology is a disorder of glycine metabolism, which leads to the accumulation of this neurotransmitter in the central nervous system and its toxicity. Glycine, although an inhibitory neurotransmitter, in high concentrations can cause neuropsychiatric disorders, seizures, coordination and movement disorders. The disease can occur both in childhood and adulthood, and the clinical picture varies depending on the time of onset and the severity of the metabolic disorder.<\/p>\n

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