{"id":11270,"date":"2025-07-27T03:25:55","date_gmt":"2025-07-27T01:25:55","guid":{"rendered":"https:\/\/valintermed.com\/?p=11270"},"modified":"2025-07-27T03:25:55","modified_gmt":"2025-07-27T01:25:55","slug":"fatalnaya-semeynaya-bessonnitsa","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/fatal-family-insomnia\/","title":{"rendered":"Fatal Familial Insomnia"},"content":{"rendered":"
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Fatal familial insomnia (FFI) is an extremely rare genetic disorder characterized by progressive insomnia that leads to serious impairment of body functions. The disease is caused by mutations in the PRNP gene, responsible for the synthesis of a prion protein, which leads to irreversible changes in the structure and function of neurons. Initial symptoms of FFI may occur in middle age and include increased insomnia, changes in mental state, autonomic disorders, and deterioration of cognitive functions. Further progression of the disease leads to severe dysfunction of mental and physical processes, up to and including death.<\/p>\n

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