{"id":11250,"date":"2025-07-27T04:25:30","date_gmt":"2025-07-27T02:25:30","guid":{"rendered":"https:\/\/valintermed.com\/?p=11250"},"modified":"2025-07-27T04:25:30","modified_gmt":"2025-07-27T02:25:30","slug":"sindrom-felti","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/felti-syndrome\/","title":{"rendered":"Felty&#039;s syndrome"},"content":{"rendered":"<div class=\"fpm_start\"><\/div>\n<p>Felty&#039;s syndrome is a relatively rare but serious autoimmune disease that is a complex of clinical manifestations associated with seropositive rheumatoid arthritis, hypersplenism and neutropenia. This syndrome was first described in 1924 and tends to have an early periodic manifestation in the form of severe inflammatory changes in the joints, subsequently leading to deformations and persistent loss of function. Mostly women aged 30 to 50 years are affected. The most pronounced clinical spectrum includes the body&#039;s ability to produce antibodies and the subsequent development of various infections, which is directly proportional to the adequacy of the functional indicators of the immune system. These pathological changes can significantly worsen the quality of life of patients and require a comprehensive approach to diagnosis and treatment in order to minimize the consequences of the disease.<\/p>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_85 counter-flat ez-toc-counter ez-toc-light-blue ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Content<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 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href=\"https:\/\/valintermed.com\/en\/medlibrary\/felti-syndrome\/#%D0%98%D1%81%D1%82%D0%BE%D1%80%D0%B8%D1%8F_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F_%D0%B8_%D0%B8%D0%BD%D1%82%D0%B5%D1%80%D0%B5%D1%81%D0%BD%D1%8B%D0%B5_%D0%B8%D1%81%D1%82%D0%BE%D1%80%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B8%D0%B5_%D1%84%D0%B0%D0%BA%D1%82%D1%8B\" >History of the disease and interesting historical facts<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/felti-syndrome\/#%D0%AD%D0%BF%D0%B8%D0%B4%D0%B5%D0%BC%D0%B8%D0%BE%D0%BB%D0%BE%D0%B3%D0%B8%D1%8F_%D1%81%D1%82%D0%B0%D1%82%D0%B8%D1%81%D1%82%D0%B8%D0%BA%D0%B0_%D0%B2%D0%BE%D0%B7%D0%BD%D0%B8%D0%BA%D0%BD%D0%BE%D0%B2%D0%B5%D0%BD%D0%B8%D1%8F_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >Epidemiology (statistics of disease occurrence)<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/felti-syndrome\/#%D0%93%D0%B5%D0%BD%D0%B5%D1%82%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B0%D1%8F_%D0%BF%D1%80%D0%B5%D0%B4%D1%80%D0%B0%D1%81%D0%BF%D0%BE%D0%BB%D0%BE%D0%B6%D0%B5%D0%BD%D0%BD%D0%BE%D1%81%D1%82%D1%8C_%D0%BA_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%BC%D1%83_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8E\" >Genetic predisposition to this disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/felti-syndrome\/#%D0%A4%D0%B0%D0%BA%D1%82%D0%BE%D1%80%D1%8B_%D1%80%D0%B8%D1%81%D0%BA%D0%B0_%D0%B2%D0%BE%D0%B7%D0%BD%D0%B8%D0%BA%D0%BD%D0%BE%D0%B2%D0%B5%D0%BD%D0%B8%D1%8F_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >Risk factors for the development of this disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/felti-syndrome\/#%D0%94%D0%B8%D0%B0%D0%B3%D0%BD%D0%BE%D1%81%D1%82%D0%B8%D0%BA%D0%B0_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >Diagnosis of this disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/felti-syndrome\/#%D0%9B%D0%B5%D1%87%D0%B5%D0%BD%D0%B8%D0%B5\" >Treatment<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/felti-syndrome\/#%D0%A1%D0%BF%D0%B8%D1%81%D0%BE%D0%BA_%D0%BB%D0%B5%D0%BA%D0%B0%D1%80%D1%81%D1%82%D0%B2_%D0%BF%D1%80%D0%B8%D0%BC%D0%B5%D0%BD%D1%8F%D0%B5%D0%BC%D1%8B%D1%85_%D0%B4%D0%BB%D1%8F_%D0%BB%D0%B5%D1%87%D0%B5%D0%BD%D0%B8%D1%8F_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >List of medications used to treat this disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/felti-syndrome\/#%D0%9C%D0%BE%D0%BD%D0%B8%D1%82%D0%BE%D1%80%D0%B8%D0%BD%D0%B3_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >Disease monitoring<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/felti-syndrome\/#%D0%92%D0%BE%D0%B7%D1%80%D0%B0%D1%81%D1%82%D0%BD%D1%8B%D0%B5_%D0%BE%D1%81%D0%BE%D0%B1%D0%B5%D0%BD%D0%BD%D0%BE%D1%81%D1%82%D0%B8_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\" >Age-related features of the disease<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/felti-syndrome\/#%D0%92%D0%BE%D0%BF%D1%80%D0%BE%D1%81%D1%8B_%D0%B8_%D0%BE%D1%82%D0%B2%D0%B5%D1%82%D1%8B\" >Questions and Answers<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/valintermed.com\/en\/medlibrary\/felti-syndrome\/#%D0%A1%D0%BE%D0%B2%D0%B5%D1%82%D1%8B_%D0%BE%D1%82_%D0%B4%D0%BE%D0%BA%D1%82%D0%BE%D1%80%D0%B0_%D0%9E%D0%BB%D0%B5%D0%B3%D0%B0_%D0%9A%D0%BE%D1%80%D0%B6%D0%B8%D0%BA%D0%BE%D0%B2%D0%B0\" >Advice from Dr. Oleg Korzhikov<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"%D0%98%D1%81%D1%82%D0%BE%D1%80%D0%B8%D1%8F_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F_%D0%B8_%D0%B8%D0%BD%D1%82%D0%B5%D1%80%D0%B5%D1%81%D0%BD%D1%8B%D0%B5_%D0%B8%D1%81%D1%82%D0%BE%D1%80%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B8%D0%B5_%D1%84%D0%B0%D0%BA%D1%82%D1%8B\"><\/span>History of the disease and interesting historical facts<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Felty syndrome was first described by Dr. Walter Felty in 1924, who analyzed cases of patients with rare manifestations of coexisting rheumatoid arthritis and neutropenia. Over the next century, there was considerable debate and controversy about the clinical definition of the syndrome, as well as its true prevalence and pathogenesis. In the 1970s, the syndrome began to emerge as a distinct disorder when studies were conducted that supported Felty&#039;s original ideas about the correlation between seroproduction, neutropenia, and inflammation. Interestingly, in the 1990s, a hereditary form of Felty syndrome was described, further cementing its reputation as an important component of reflex mechanisms of autoimmunity.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%AD%D0%BF%D0%B8%D0%B4%D0%B5%D0%BC%D0%B8%D0%BE%D0%BB%D0%BE%D0%B3%D0%B8%D1%8F_%D1%81%D1%82%D0%B0%D1%82%D0%B8%D1%81%D1%82%D0%B8%D0%BA%D0%B0_%D0%B2%D0%BE%D0%B7%D0%BD%D0%B8%D0%BA%D0%BD%D0%BE%D0%B2%D0%B5%D0%BD%D0%B8%D1%8F_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>Epidemiology (statistics of disease occurrence)<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Felty syndrome occurs in the population with a frequency of approximately 1-3% among patients with rheumatoid arthritis, but its true prevalence may be lower given possible diagnostic errors. Most cases are reported among women, especially those of reproductive age. Studies show that the disease is most common in individuals with a genetic predisposition to autoimmune disorders, which is due to certain genetic polymorphisms. In addition, some studies indicate an increased incidence in certain population groups, such as the elderly, which may signal the importance of monitoring and early diagnosis in this category.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%93%D0%B5%D0%BD%D0%B5%D1%82%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B0%D1%8F_%D0%BF%D1%80%D0%B5%D0%B4%D1%80%D0%B0%D1%81%D0%BF%D0%BE%D0%BB%D0%BE%D0%B6%D0%B5%D0%BD%D0%BD%D0%BE%D1%81%D1%82%D1%8C_%D0%BA_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%BC%D1%83_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8E\"><\/span>Genetic predisposition to this disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>There are certain genes that may be associated with the development of Felty&#039;s syndrome, including genes associated with the XLA-DRB1 syndrome, which plays a key role in the immune response. In particular, it has been established that polymorphisms of these genes can affect the level of antibodies and the severity of the disease. Studies have also found that some mutations in genes responsible for the production of cytokines can activate inflammatory processes, which in turn leads to neutropenia and hypersplenism. Thus, hereditary predisposition is one of the key factors contributing to this disease.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%A4%D0%B0%D0%BA%D1%82%D0%BE%D1%80%D1%8B_%D1%80%D0%B8%D1%81%D0%BA%D0%B0_%D0%B2%D0%BE%D0%B7%D0%BD%D0%B8%D0%BA%D0%BD%D0%BE%D0%B2%D0%B5%D0%BD%D0%B8%D1%8F_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>Risk factors for the development of this disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Various factors can contribute to the development of Felty&#039;s syndrome, including both physical and chemical ones. The main risk factors include:<\/p>\n<ul>\n<li>Stress and emotional stress.<\/li>\n<li>Infectious diseases, especially viral ones such as hepatitis or HIV.<\/li>\n<li>History of autoimmune diseases (eg, systemic lupus erythematosus).<\/li>\n<li>Smoking and drinking alcohol.<\/li>\n<li>Environmental factors - exposure to toxic substances such as myrcime and benzene compounds.<\/li>\n<li>Age over 50 years combined with genetic predisposition.<\/li>\n<\/ul>\n<p>Understanding these risk factors is important for developing strategies for prevention and early detection of Felty syndrome.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%94%D0%B8%D0%B0%D0%B3%D0%BD%D0%BE%D1%81%D1%82%D0%B8%D0%BA%D0%B0_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>Diagnosis of this disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Diagnosis of Felty&#039;s syndrome requires a thorough clinical examination and a number of laboratory tests. The main symptoms of this disease include:<\/p>\n<ul>\n<li>Constant pain symptoms in the joints and their inflammation.<\/li>\n<li>Decreased levels of leukocytes and neutrophils in tests.<\/li>\n<li>Enlarged spleen and liver on examination.<\/li>\n<li>Frequent infections with little visual activity.<\/li>\n<\/ul>\n<p>Laboratory tests include:<\/p>\n<ul>\n<li>Complete blood count to detect neutropenia.<\/li>\n<li>Determination of the level of inflammatory markers (C-reactive protein, anticardiolipin antibodies).<\/li>\n<li>Rheumatoid factor antibody tests.<\/li>\n<li>Detection of abnormalities in liver parameters.<\/li>\n<\/ul>\n<p>Radiological examinations such as ultrasound may help to identify changes in the spleen and other organs. Differential diagnosis includes exclusion of other acute and chronic infectious diseases and hematopoietic disorders.<\/p><script data-noptimize=\"\" data-wpfc-render=\"false\">\nfpm_start( \"true\" );\n<\/script>\n\n<h2><span class=\"ez-toc-section\" id=\"%D0%9B%D0%B5%D1%87%D0%B5%D0%BD%D0%B8%D0%B5\"><\/span>Treatment<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Treatment of Felty&#039;s syndrome requires a comprehensive approach and may include both conservative and surgical methods. General treatment includes:<\/p>\n<ul>\n<li>Steroids and nonsteroidal anti-inflammatory drugs to relieve inflammation.<\/li>\n<li>Immunomodulators for correction of immune system functions.<\/li>\n<li>Antibiotics for the prevention and treatment of infections.<\/li>\n<\/ul>\n<p>Pharmacological treatment focuses on the underlying rheumatoid arthritis, including the use of gold mineral salts and D-penicillamine. Surgery may be required in cases of severe spleen enlargement or other complications, which may include removal of the spleen. Other approaches include physical therapy and rehabilitation to improve quality of life.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%A1%D0%BF%D0%B8%D1%81%D0%BE%D0%BA_%D0%BB%D0%B5%D0%BA%D0%B0%D1%80%D1%81%D1%82%D0%B2_%D0%BF%D1%80%D0%B8%D0%BC%D0%B5%D0%BD%D1%8F%D0%B5%D0%BC%D1%8B%D1%85_%D0%B4%D0%BB%D1%8F_%D0%BB%D0%B5%D1%87%D0%B5%D0%BD%D0%B8%D1%8F_%D0%B4%D0%B0%D0%BD%D0%BD%D0%BE%D0%B3%D0%BE_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>List of medications used to treat this disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Medications used to treat Felty&#039;s syndrome include:<\/p>\n<ul>\n<li>Methotrexate.<\/li>\n<li>Hydroxychloroquine.<\/li>\n<li>Leflunomide.<\/li>\n<li>Glucocorticosteroids.<\/li>\n<li>Repeated antibiotics (eg, amoxicillin).<\/li>\n<li>Monoclonal antibodies (tocilizumab).<\/li>\n<\/ul>\n<p>Effective choice of therapy is based on a thorough analysis of the patient&#039;s condition and his individual characteristics.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%9C%D0%BE%D0%BD%D0%B8%D1%82%D0%BE%D1%80%D0%B8%D0%BD%D0%B3_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>Disease monitoring<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Care of patients with Felty syndrome requires regular assessment and monitoring to prevent complications and improve quality of life. Key monitoring steps include:<\/p>\n<ul>\n<li>Periodic blood tests to monitor white blood cell levels.<\/li>\n<li>Monitoring of spleen and liver functions using ultrasound.<\/li>\n<li>Assessment of the clinical condition and the degree of inflammatory processes.<\/li>\n<\/ul>\n<p>The prognosis of the disease varies depending on the severity and nature of the course, but timely treatment can significantly improve the quality of life of patients. Complications may include severe infections, sepsis, and the development of secondary autoimmune diseases.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%92%D0%BE%D0%B7%D1%80%D0%B0%D1%81%D1%82%D0%BD%D1%8B%D0%B5_%D0%BE%D1%81%D0%BE%D0%B1%D0%B5%D0%BD%D0%BD%D0%BE%D1%81%D1%82%D0%B8_%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F\"><\/span>Age-related features of the disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Felty&#039;s syndrome is characterized by differences in manifestations and severity depending on the age category. In young patients, the disease usually manifests itself acutely with pronounced symptoms, while in older people it can proceed more latent, which sometimes complicates diagnosis. At an early age, patients more often suffer from infectious complications, while among the elderly, exhaustion and concomitant autoimmune diseases predominate.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%D0%92%D0%BE%D0%BF%D1%80%D0%BE%D1%81%D1%8B_%D0%B8_%D0%BE%D1%82%D0%B2%D0%B5%D1%82%D1%8B\"><\/span>Questions and Answers<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<ul>\n<li><strong>What are the main symptoms of Felty syndrome?<\/strong><br \/>\nThe main symptoms are rheumatoid arthritis, neutropenia, enlarged spleen and frequent infections.<\/li>\n<li><strong>How common is Felty&#039;s syndrome?<\/strong><br \/>\nFelty syndrome is seen in 1-3% patients with rheumatoid arthritis.<\/li>\n<li><strong>How is Felty syndrome diagnosed?<\/strong><br \/>\nDiagnosis includes blood tests, ultrasound and radiological examinations, and assessment of clinical signs.<\/li>\n<li><strong>Is it possible to completely cure Felty&#039;s syndrome?<\/strong><br \/>\nThe syndrome cannot be completely cured, but symptoms can be controlled and quality of life can be improved.<\/li>\n<li><strong>What is the role of genetics in the development of Felty syndrome?<\/strong><br \/>\nGenetic predisposition, in particular HLA-DRB1 gene polymorphisms, plays a role in the development of this syndrome.<\/li>\n<\/ul>\n<h2><span class=\"ez-toc-section\" id=\"%D0%A1%D0%BE%D0%B2%D0%B5%D1%82%D1%8B_%D0%BE%D1%82_%D0%B4%D0%BE%D0%BA%D1%82%D0%BE%D1%80%D0%B0_%D0%9E%D0%BB%D0%B5%D0%B3%D0%B0_%D0%9A%D0%BE%D1%80%D0%B6%D0%B8%D0%BA%D0%BE%D0%B2%D0%B0\"><\/span>Advice from Dr. Oleg Korzhikov<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Patients with Felty&#039;s syndrome need to pay special attention to their condition and adjust their lifestyle. Here are some important tips:<\/p>\n<ul>\n<li>Get regular medical checkups to monitor your health.<\/li>\n<li>Pay attention to your diet: it should be balanced and rich in vitamins and minerals.<\/li>\n<li>Avoid stress, which can worsen the course of the disease.<\/li>\n<li>Maintain a physical activity regimen that takes into account your limitations to maintain overall tone.<\/li>\n<li>Monitor the level of infectious diseases during cold season and get vaccinated.<\/li>\n<\/ul>\n<p>By following these recommendations, you can significantly increase the length and quality of your life.<\/p>\n<div class=\"fpm_end\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Felty&#039;s syndrome is a relatively rare but serious autoimmune disease that represents a complex of clinical manifestations associated with seropositive rheumatoid arthritis.<\/p>","protected":false},"author":1,"featured_media":18223,"comment_status":"open","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[298],"tags":[],"class_list":["post-11250","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medlibrary"],"_links":{"self":[{"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/posts\/11250","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/comments?post=11250"}],"version-history":[{"count":1,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/posts\/11250\/revisions"}],"predecessor-version":[{"id":15965,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/posts\/11250\/revisions\/15965"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/media\/18223"}],"wp:attachment":[{"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/media?parent=11250"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/categories?post=11250"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/valintermed.com\/en\/wp-json\/wp\/v2\/tags?post=11250"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}