{"id":11227,"date":"2025-07-27T05:27:38","date_gmt":"2025-07-27T03:27:38","guid":{"rendered":"https:\/\/valintermed.com\/?p=11227"},"modified":"2025-07-27T05:27:38","modified_gmt":"2025-07-27T03:27:38","slug":"semeynyy-defitsit-lpvp","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/family-deficit-lpvp\/","title":{"rendered":"Familial HDL deficiency"},"content":{"rendered":"
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Familial HDL (high-density lipoprotein) deficiency is a rare hereditary disease characterized by severe hypolipidemia with deficiency or absence of HDL, as well as high levels of triglycerides and cholesterol in the blood. High-density lipoproteins play a key role in the transport of cholesterol, facilitating its elimination from the body. In this regard, their deficiency leads to a number of cardiovascular diseases, as well as the possibility of the formation of atherosclerotic plaques. The disease is most often caused by genetic mutations that lead to disruption of lipoprotein metabolism and represent an important problem both in clinical practice and in research.<\/p>\n

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