{"id":11220,"date":"2025-07-27T05:56:36","date_gmt":"2025-07-27T03:56:36","guid":{"rendered":"https:\/\/valintermed.com\/?p=11220"},"modified":"2025-07-27T05:56:36","modified_gmt":"2025-07-27T03:56:36","slug":"semeynaya-smeshannaya-krioglobulinemiya","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/family-mixed-cryoglobulinemia\/","title":{"rendered":"Familial mixed cryoglobulinemia"},"content":{"rendered":"
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Familial mixed cryoglobulinemia is a rare disorder characterized by the presence of cryoglobulins in the serum that, when cooled, cause aggregation and precipitation, leading to various clinical manifestations. This syndrome is often associated with concomitant infections, autoimmune pathologies, and some types of cancer. Mixed cryoglobulinemias can be primary, occurring without an apparent cause, or secondary, developing against the background of other diseases, such as chronic viral hepatitis, Henoch-Schonlein disease, or systemic lupus erythematosus. This disease can manifest itself through skin rashes, arthritis, neuropathy, and can affect various organs, including the kidneys. <\/p>\n

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