{"id":11173,"date":"2025-07-27T08:26:35","date_gmt":"2025-07-27T06:26:35","guid":{"rendered":"https:\/\/valintermed.com\/?p=11173"},"modified":"2025-07-27T08:26:35","modified_gmt":"2025-07-27T06:26:35","slug":"defitsit-fruktozo-1-6-bisfosfatazy","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/fructozo-deficiency-1-6-bisphosphatase\/","title":{"rendered":"Fructose-1,6-bisphosphatase deficiency"},"content":{"rendered":"
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Fructose-1,6-bisphosphatase (FBP) deficiency is a rare hereditary disorder that belongs to a group of metabolic disorders caused by a deficiency of an enzyme that plays a key role in glycolysis and gluconeogenesis. Deficiency of this enzyme leads to a disruption of carbohydrate metabolism, which in turn causes an accumulation of intermediate metabolites and impairs the energy supply of cells. The main manifestations of the disease are hypoglycemia, lactatosis, and an increase in the level of fats in the liver and kidneys. This condition usually manifests itself in childhood, but sometimes it can remain unnoticed until later.<\/p>\n

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