{"id":11170,"date":"2025-07-27T08:28:03","date_gmt":"2025-07-27T06:28:03","guid":{"rendered":"https:\/\/valintermed.com\/?p=11170"},"modified":"2025-07-27T08:28:03","modified_gmt":"2025-07-27T06:28:03","slug":"defitsit-faktora-12","status":"publish","type":"post","link":"https:\/\/valintermed.com\/en\/medlibrary\/deficit-factor-12\/","title":{"rendered":"Factor 12 deficiency"},"content":{"rendered":"
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Factor 12 deficiency, or activator of non-activated plasma prothrombin deficiency, is a rare genetic condition associated with hemostasis disorder caused by a lack of factor XII of the coagulation system. This factor, also known as Hageman factor, plays a key role in the activation of the coagulation cascade, in addition to its involvement in the inflammatory and fibrinolytic systems. Although its deficiency does not usually lead to significant thrombotic events, it can manifest as a predominantly hemorrhagic state, which requires adequate clinical monitoring and support. <\/p>\n

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